Quality control

Which release tests apply to which tracer, and what equipment each test needs. Monograph numbers are references only — the texts are copyrighted and are not reproduced. How the derived entries work

Of 309 entries, 15 rest on a monograph and 279 carry at least one preliminary mark.

Taken from a pharmacopoeial monograph, cited by number Derived from what the published synthesis states Preliminary — inferred from compound class and isotope, not yet from data

Tracer	Ph. Eur.	Appearance	pH	RCP HPLC	RCP TLC	HPLC cond.	Residual solvents (GC)	Kryptofix	Radionuclidic (HPGe)	Half-life	Activity	Endotoxins (LAL)	Sterility	Filter integrity	HPLC UV	HPLC ECD	Molar activity	Metal impurities	Ge-68 breakthrough	Osmolality	Lu-177m
[18F]FDG	1325	×	×	×	×	×	×	×	×	×	×	×	×	×
[18F]FDOPA	1918 (electrophilic route); 2481 (nucleophilic route)	×	×	×			×		×	×	×	×	×	×	×	×
[18F]FET	2466	×	×	×			×	×	×	×	×	×	×	×	×
[18F]FMISO	2459	×	×	×			×	×	×	×	×	×	×	×	×
[18F]FLT	2460	×	×	×			×	×	×	×	×	×	×	×	×
[18F]PSMA-1007	3116	×	×	×			×	×	×	×	×	×	×	×	×		×
[18F]DCFPyL	no specific monograph	×	×	×			×	×	×	×	×	×	×	×	×		×
[18F]NaF	2100	×	×	×	×				×	×	×	×	×	×
[18F]FCH	2793	×	×	×		×	×		×	×	×	×	×	×
[11C]methionine	1617	×	×	×			×		×	×	×	×	×	×	×
[11C]choline	2462	×	×	×		×	×		×	×	×	×	×	×
[11C]PiB	no specific monograph	×	×	×			×		×	×	×	×	×	×	×		×
[68Ga]Ga-PSMA-11	3044	×	×	×	×				×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTATATE	3050	×	×	×	×				×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTA-TOC	2482	×	×	×	×				×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-FAPI-46	no specific monograph	×	×	×	×				×	×	×	×	×	×	×		×	×	×
[177Lu]Lu-PSMA-617	no specific monograph	×	×	×	×				×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-DOTATATE	no specific monograph	×	×	×	×				×	×	×	×	×	×	×		×	×		×	×
[13N]Ammonia	1492	×	×		×				×	×	×	×	×	×
[68Ga]GaCl3	2464 (generator-produced); 3109 (accelerator-produced)	×	×						×	×	×							×
[64Cu]Cu-DOTATATE	—	×	×	×					×	×	×	×	×	×	×		×	×
[18F]MK-6240	—	×	×	×	×				×	×	×	×	×	×	×
[18F]GE-180	—	×	×	×	×				×	×	×	×	×	×	×
[18F]GE-179	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FSPG	—	×	×	×	×	×			×	×	×	×	×	×
[18F]FRPG	—	×	×	×	×	×			×	×	×	×	×	×
[18F]FPIA	—	×	×	×	×	×			×	×	×	×	×	×
[18F]ICMT-11	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FETrp	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FTYR	—	×	×	×	×				×	×	×	×	×	×	×
[18F]TFB	—	×	×	×	×	×			×	×	×	×	×	×
[18F]VM4-037	—	×	×	×	×				×	×	×	×	×	×	×
[18F]THK5351	—	×	×	×	×				×	×	×	×	×	×	×
[18F]Fluciclatide	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FBEM	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FET-bAG-TOCA	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]AlF-OncoFAP-NODAGA	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]AlF-OncoFAP-NOTA	—	×	×	×	×				×	×	×	×	×	×	×		×
[68Ga]Ga-OncoFAP-DOTAGA	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-OncoFAP-NODAGA	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-OncoFAP-NOTA	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[177Lu]Lu-OncoFAP-DOTAGA	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[68Ga]Ga-RM2	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[111In]In-RM2	—	×	×	×					×	×	×	×	×	×	×		×	×
[111In]In-PSMA-617	—	×	×	×					×	×	×	×	×	×	×		×	×
[61Cu]CuCl2	—	×	×						×	×	×	×	×	×				×
[18F]BPAM121	—	×	×	×	×				×	×	×	×	×	×	×
[18F]DK222	—	×	×	×	×				×	×	×	×	×	×	×
[18F]AH113804	—	×	×	×	×				×	×	×	×	×	×	×
[18F]GE-226	—	×	×	×	×				×	×	×	×	×	×	×
[18F]SqFLT	—	×	×	×	×				×	×	×	×	×	×	×
[18F]TTCO-IL2	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FSO3-PSMA	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]RSO2CF2H	—	×	×	×	×				×	×	×	×	×	×	×
2-[18F]fluoroethyl tosylate	—	×	×	×	×				×	×	×	×	×	×	×
[18F]fluoromethyl tosylate	—	×	×	×	×				×	×	×	×	×	×	×
3-[18F]fluoropropyl tosylate	—	×	×	×	×				×	×	×	×	×	×	×
[18F]SFB	—	×	×	×	×		×		×	×	×	×	×	×	×
[18F]FBA	—	×	×	×	×				×	×	×	×	×	×	×
[18F]F-Py-TFP	—	×	×	×	×				×	×	×	×	×	×	×
[11C]6-bromopurine	—	×	×	×	×				×	×	×	×	×	×	×
[11C]ABP688	—	×	×	×	×				×	×	×	×	×	×	×
[11C]acetate	—	×	×	×	×				×	×	×	×	×	×	×		×
[11C]acetoacetate	—	×	×	×	×				×	×	×	×	×	×	×		×
[11C]AMT	—	×	×	×	×				×	×	×	×	×	×	×
[11C]AZ13198083	—	×	×	×	×				×	×	×	×	×	×	×
[11C]carfentanil	—	×	×	×	×				×	×	×	×	×	×	×
[11C]CP31398	—	×	×	×	×				×	×	×	×	×	×	×
[11C]CPPC	—	×	×	×	×				×	×	×	×	×	×	×
[11C]DASB	—	×	×	×	×				×	×	×	×	×	×	×
[11C]ER176	—	×	×	×	×				×	×	×	×	×	×	×
[11C]erlotinib	—	×	×	×	×				×	×	×	×	×	×	×
[11C]evobrutinib	—	×	×	×	×				×	×	×	×	×	×	×
[11C]FMZ	—	×	×	×	×				×	×	×	×	×	×	×
[11C]GR103545	—	×	×	×	×				×	×	×	×	×	×	×
[11C]ibrutinib	—	×	×	×	×				×	×	×	×	×	×	×
[11C]KIn83	—	×	×	×	×				×	×	×	×	×	×	×
[11C]L-deprenyl-D2	—	×	×	×	×				×	×	×	×	×	×	×
[11C]L-glutamine	—	×	×	×	×	×			×	×	×	×	×	×
[11C]LY2795050	—	×	×	×	×				×	×	×	×	×	×	×
[11C]Me-NB1	—	×	×	×	×				×	×	×	×	×	×	×
10-[11C]methoxy-20(S)-camptothecin	—	×	×	×	×				×	×	×	×	×	×	×
[11C]MTP38	—	×	×	×	×				×	×	×	×	×	×	×
[11C]pbb3	—	×	×	×	×				×	×	×	×	×	×	×
[11C]PBR28	—	×	×	×	×				×	×	×	×	×	×	×
[11C]PD153035	—	×	×	×	×				×	×	×	×	×	×	×
[11C](+)-PHNO	—	×	×	×	×				×	×	×	×	×	×	×
[11C]phosgene	—	×	×	×	×				×	×	×	×	×	×	×
[11C]PK68	—	×	×	×	×				×	×	×	×	×	×	×
[11C]PS13	—	×	×	×	×				×	×	×	×	×	×	×
[11C]raclopride	—	×	×	×	×				×	×	×	×	×	×	×
[11C]RSR-056	—	×	×	×	×				×	×	×	×	×	×	×
[11C]SSI-4	—	×	×	×	×				×	×	×	×	×	×	×
[11C]TGN-020	—	×	×	×	×				×	×	×	×	×	×	×
[11C]UCB-J	—	×	×	×	×				×	×	×	×	×	×	×
[11C]YM155	—	×	×	×	×				×	×	×	×	×	×	×
[64Cu]Cu-FAPI-2286	—	×	×	×					×	×	×	×	×	×	×		×	×
[64Cu]Cu-sartate	—	×	×	×					×	×	×	×	×	×	×		×	×
[18F]6-O-desmethyl-diprenorphine	—	×	×	×	×				×	×	×	×	×	×	×
[18F]ADPM06	—	×	×	×	×				×	×	×	×	×	×	×
[18F]AF78	—	×	×	×	×				×	×	×	×	×	×	×
[18F]AG-120	—	×	×	×	×				×	×	×	×	×	×	×
[18F]AlF	—	×	×	×	×				×	×	×	×	×	×	×
[18F]AlF-NOTA-ubiquicidin 29-41	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]AlF-3p-C-NETA-TATE	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]AlF-FAPI-74	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]AlF-NOTA-FAPI-04	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]AlF-NOTA-octreotide	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]AlF-NOTA-RD2	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]AlF-OncoFAP	—	×	×	×	×				×	×	×	×	×	×	×
[18F]AlF-P16-093	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]AmBF3-TATE	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]ApaScan	—	×	×	×	×				×	×	×	×	×	×	×
[18F]AQ28A	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]AV-45	—	×	×	×	×				×	×	×	×	×	×	×
[18F]BIBD-239	—	×	×	×	×				×	×	×	×	×	×	×
[18F]bromofluoromethane-d2	—	×	×	×	×				×	×	×	×	×	×	×
[18F]BTK-1	—	×	×	×	×				×	×	×	×	×	×	×
[18F]CbR	—	×	×	×	×				×	×	×	×	×	×	×
[18F]cGBP4F	—	×	×	×	×				×	×	×	×	×	×	×
[18F]d2-tosylate	—	×	×	×	×				×	×	×	×	×	×	×
[18F]DAA1106	—	×	×	×	×				×	×	×	×	×	×	×
[18F]Dolutegravir	—	×	×	×	×				×	×	×	×	×	×	×
[18F]DPA-714	—	×	×	×	×				×	×	×	×	×	×	×
[18F]DPA-C5yne	—	×	×	×	×				×	×	×	×	×	×	×
[18F]ef5	—	×	×	×	×				×	×	×	×	×	×	×
[18F]EKZ-001	—	×	×	×	×				×	×	×	×	×	×	×
[18F]F-A-85380	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FACBC	—	×	×	×	×				×	×	×	×	×	×	×
[18F]fallypride	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]FAPI-42	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]FAPI-74	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]FAZA	—	×	×	×	×		×		×	×	×	×	×	×	×
[18F]fluoroazomycin-2'-deoxyribofuranoside	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FB-2BD42	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FB-4AH29	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FB-A20FMDV2	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FBAM	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FBEM-Cys-H4	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FB(ePEG12)12-exendin-4	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]FB-HER2	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FB-IL2	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FBNA	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FBnTP	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FBPA	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FB-S100s	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FCPPC	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FDDNP	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FDHT	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]FDR	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FEAU	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FEDAA1106	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FE-DPN	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FE-PE2I	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FEPPA	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FES	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FG-CP31398	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FGln	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FHBG	—	×	×	×	×				×	×	×	×	×	×	×
[18F]fiau	—	×	×	×	×				×	×	×	×	×	×	×
[18F]Florbetaben	—	×	×	×	×				×	×	×	×	×	×	×
[18F]fludarabine	—	×	×	×	×				×	×	×	×	×	×	×
[18F]fluoro-2-deoxy-D-galactose	—	×	×	×	×	×			×	×	×	×	×	×
[18F]fluoro-3-(2(S)-azetidinylmethoxy)pyridine	—	×	×	×	×				×	×	×	×	×	×	×
[18F]fluoroacetate	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]fluorocellobiose	—	×	×	×	×	×			×	×	×	×	×	×
[18F]fluoroethylazide	—	×	×	×	×				×	×	×	×	×	×	×
[18F]fluoroethylcholine	—	×	×	×	×	×	×		×	×	×	×	×	×
[18F]fluorogabapentin	—	×	×	×	×				×	×	×	×	×	×	×
[18F]fluoromannitol	—	×	×	×	×	×			×	×	×	×	×	×
2-[18F]fluoro-myo-inositol	—	×	×	×	×	×			×	×	×	×	×	×
[18F]fluorophenylalanine	—	×	×	×	×				×	×	×	×	×	×	×
6-[18F]fluoro-3-(pyridin-3-yl)-1H-indole	—	×	×	×	×				×	×	×	×	×	×	×
[18F]fluorosulfate	—	×	×	×	×	×			×	×	×	×	×	×
[18F]FluorThanatrace	—	×	×	×	×				×	×	×	×	×	×	×
[18F]fluspidine	—	×	×	×	×				×	×	×	×	×	×	×
[18F]flutemetamol	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FMAU	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FMeNER-D2	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FMN3PA	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FMN3PU	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FMPEP-d2	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FMZ	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FP-CIT	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FP-cRGDySO3	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]FPEB	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FP-ERGDySO3	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]FPG-IL4	—	×	×	×	×				×	×	×	×	×	×	×
[18F]F-PRGD2	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]F-PSMA-617-NODA	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]F-PSMA-617-RESCA	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]FP-TZTP	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FSW-100	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FTC-146	—	×	×	×	×				×	×	×	×	×	×	×
[18F]FTHA	—	×	×	×	×				×	×	×	×	×	×	×
16-[18F]fluoro-4-thia-palmitic acid	—	×	×	×	×				×	×	×	×	×	×	×
[18F]GTP1	—	×	×	×	×				×	×	×	×	×	×	×
[18F]HX4	—	×	×	×	×				×	×	×	×	×	×	×
[18F]JK-PSMA-7	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]JMV5763	—	×	×	×	×				×	×	×	×	×	×	×
[18F]JNJ-46356479	—	×	×	×	×				×	×	×	×	×	×	×
[18F]JNJ64413739	—	×	×	×	×				×	×	×	×	×	×	×
[18F]K10-008	—	×	×	×	×				×	×	×	×	×	×	×
[18F]LBT999	—	×	×	×	×				×	×	×	×	×	×	×
[18F]L-Glutamic	—	×	×	×	×	×			×	×	×	×	×	×
[18F]L-tryptophan	—	×	×	×	×				×	×	×	×	×	×	×
[18F]mBPET-1	—	×	×	×	×				×	×	×	×	×	×	×
[18F]MC225	—	×	×	×	×				×	×	×	×	×	×	×
[18F]MEL050	—	×	×	×	×				×	×	×	×	×	×	×
[18F]mG4P027	—	×	×	×	×				×	×	×	×	×	×	×
[18F]MIPS15692	—	×	×	×	×				×	×	×	×	×	×	×
(R)-2-(N-benzyl-4-(2-[18F]fluoroethoxy)phenylsulphonamido)-N-hydroxy-3-methylbutanamide	—	×	×	×	×				×	×	×	×	×	×	×
[18F]NAV4694	—	×	×	×	×				×	×	×	×	×	×	×
[18F]NOTA-ABY-030	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]NS10743	—	×	×	×	×				×	×	×	×	×	×	×
[18F]OP-801	—	×	×	×	×				×	×	×	×	×	×	×
[18F]P10A-1910	—	×	×	×	×				×	×	×	×	×	×	×
[18F]PARPi	—	×	×	×	×				×	×	×	×	×	×	×
[18F]PBR06	—	×	×	×	×				×	×	×	×	×	×	×
[18F]PBR102	—	×	×	×	×				×	×	×	×	×	×	×
[18F]PBR111	—	×	×	×	×				×	×	×	×	×	×	×
[18F]PEG4-1-thiol	—	×	×	×	×				×	×	×	×	×	×	×
[18F]pi2620	—	×	×	×	×				×	×	×	×	×	×	×
[18F]PM-PBB3	—	×	×	×	×				×	×	×	×	×	×	×
[18F](E)-PSS232	—	×	×	×	×				×	×	×	×	×	×	×
[18F]rhPSMA-7	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]ro948	—	×	×	×	×				×	×	×	×	×	×	×
[18F]SiTATE	—	×	×	×	×				×	×	×	×	×	×	×		×
[18F]SMBT-1	—	×	×	×	×				×	×	×	×	×	×	×
[18F]SO2F2	—	×	×	×	×				×	×	×	×	×	×	×
[18F]SynVesT-1	—	×	×	×	×				×	×	×	×	×	×	×
[18F]T807	—	×	×	×	×				×	×	×	×	×	×	×
[18F]tGBP4F	—	×	×	×	×				×	×	×	×	×	×	×
[18F]THK-5117	—	×	×	×	×				×	×	×	×	×	×	×
[18F]UCB-H	—	×	×	×	×				×	×	×	×	×	×	×
[18F]VAT	—	×	×	×	×				×	×	×	×	×	×	×
[68Ga]Ga-3p-C-NETA	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-ABY-025	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-BOT5035	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-BPAMD	—	×	×	×					×	×	×	×	×	×	×			×	×
[68Ga]Ga-citrate	—	×	×	×		×			×	×	×	×	×	×				×	×
[68Ga]Ga-D0103	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DO3A-VS-Cys40-Exendin-4	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DO3A-VS-Cys40-Tuna-2	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTA-AMBS-CPCR4	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTA-Arg3-Nal4-Gly5	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTA-CCK-66	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTA-CP04	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTA-D-Phe-Tyr3-octreotide	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTA-ECL1i	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTA-exendin-4	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTANOC	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTA-r-a-ABA-CPCR4	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTA-Siglec-9	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-DOTA-Z09591	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-EMP100	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-FAP-2286	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-FAPI	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-FAPI-02	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-FAPI-04	—	×	×	×			×		×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-FAPI-64	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-FAPI-74	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-NODAGA-exendin-4	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-NOTA-BBN2	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-OncoFAP	—	×	×	×					×	×	×	×	×	×	×			×	×
[68Ga]Ga-oxine	—	×	×	×					×	×	×	×	×	×	×			×	×
[68Ga]Ga-P16-093	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-Pentixafor	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-PSMA-I&T	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-PSMA-617	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[68Ga]Ga-TRAP-(RGD)3	—	×	×	×					×	×	×	×	×	×	×		×	×	×
[123I]beta-CIT	—	×	×	×	×				×	×	×	×	×	×	×
[123I]FP-CIT	—	×	×	×	×				×	×	×	×	×	×	×
[123I]iodoamphetamine	—	×	×	×	×				×	×	×	×	×	×	×
[123I]MIBG	—	×	×	×	×				×	×	×	×	×	×	×		×
[123I]R91150	—	×	×	×	×				×	×	×	×	×	×	×
[125I]FC-131	—	×	×	×	×				×	×	×	×	×	×	×
[125I]Pentixafor	—	×	×	×	×				×	×	×	×	×	×	×		×
[177Lu]Lu-CP04	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-CTT2001	—	×	×	×					×	×	×	×	×	×	×			×		×	×
[177Lu]Lu-DOTA-MGS5	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-DOTA-PP-F11N	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-DOTA-r-a-ABA-iodoCPCR4	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-DOTA-rhCCK-18	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-DOTA-TOC	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-FAPI	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-FAPI-04	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-FAPI-46	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-P17-087	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-P17-088	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-pentixather	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-PSMA-I&T	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-PSMA-10	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-(R)-DOTAGA-rhCCK-1	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[177Lu]Lu-rhPSMA-10	—	×	×	×					×	×	×	×	×	×	×		×	×		×	×
[212Pb]Pb-PSC-PEG2-TOC	—	×	×	×					×	×	×	×	×	×	×		×	×		×
[161Tb]Tb-3p-C-NETA	—	×	×	×					×	×	×	×	×	×	×		×	×		×
[99mTc]Tc-N4-Bombesin	—	×	×	×					×	×	×	×	×	×	×		×	×
[99mTc]Tc-N4-PSMA-12	—	×	×	×					×	×	×	×	×	×	×		×	×
[99mTc]Tc-PSMA-I&S	—	×	×	×					×	×	×	×	×	×	×		×	×
[99mTc]Tc-TcO2	—	×	×	×					×	×	×	×	×	×	×			×
[99mTc]Tc-TcO4	—	×	×	×					×	×	×	×	×	×	×			×
[90Y]Y-FAPI	—	×	×	×					×	×	×	×	×	×	×		×	×		×
[90Y]Y-FAPI-46	—	×	×	×					×	×	×	×	×	×	×		×	×		×
[89Zr]Zr-Df-IgG-800CW	—	×	×	×					×	×	×	×	×	×	×		×	×
[89Zr]Zr-DFO-girentuximab	—	×	×	×					×	×	×	×	×	×	×		×	×
[89Zr]Zr-Df-pertuzumab-800CW	—	×	×	×					×	×	×	×	×	×	×		×	×
[89Zr]Zr-TROP2	—	×	×	×					×	×	×	×	×	×	×		×	×
[89Zr]ZrCl4	—	×	×	×					×	×	×	×	×	×	×			×

Rows with an amber edge carry at least one preliminary mark: the test set was inferred from the compound class and isotope, not from a monograph or from what a paper states about the synthesis. Treat those as a starting point for scoping, never as a release specification.

What each test needs

Test	What it establishes	Equipment
Appearance / clarity and colour	Visual conformity of the solution	Visual inspection against a lit background
pH	pH within the specified range Strips accepted in many monographs for small volumes	pH meter
Radiochemical purity by HPLC	Fraction of activity present as the intended chemical form Only HPLC resolves radiolysis products; radio-TLC alone may miss them	HPLC with radiometric detector
Radiochemical purity by radio-TLC	Same as above, faster, no recovery issues	Radio-TLC scanner
UV detection on HPLC	Identity and chemical impurities of UV-active species	HPLC with UV or PDA detector
Electrochemical detection on HPLC	Chemical impurities of species with poor UV response Needed for catecholamine-type compounds	HPLC with electrochemical detector
Conductometric detection on HPLC	Ionic species not detected by UV	HPLC with conductivity detector
Chemical purity / limit of impurities	Non-radioactive impurities within limits	HPLC
Residual solvents	Acetonitrile, ethanol, ether and similar within limits Almost universal for F-18 tracers made with acetonitrile	Gas chromatograph with FID or headspace
Kryptofix 2.2.2 / phase transfer catalyst	Residual cryptand within limits Applies where K222 is used in the synthesis	TLC spot test (iodoplatinate)
Radionuclidic purity	Correct radionuclide, gamma impurities within limits Ph. Eur. commonly requires >99.9%; F-18 samples are held ~24 h to allow decay before measurement	Gamma spectrometer (HPGe)
Half-life determination	Identity of the radionuclide by decay	Dose calibrator with timer
Radioactivity concentration	Activity at reference time Requires validated geometry	Dose calibrator (activity meter)
Bacterial endotoxins	Endotoxin level below limit Released before result in most cases; retrospective for short-lived tracers	LAL tester (kinetic or gel clot)
Sterility	Absence of viable micro-organisms Always retrospective	Sterility testing (media fill / membrane filtration)
Filter integrity (bubble point)	Integrity of the sterilising filter Substitutes for pre-release sterility	Filter integrity tester
Osmolality	Isotonicity of the final formulation More often required for therapeutic and large-volume preparations	Osmometer
Molar activity	Activity per mole of compound Critical for receptor-targeted tracers with saturable targets	HPLC with UV and radiometric detection
Metal impurities	Fe, Zn, Cu and similar within limits Relevant for radiometal preparations	ICP-MS
Ge-68 breakthrough	Parent radionuclide from the generator within limits Generator-produced Ga-68 only	Gamma spectrometer after Ga-68 decay
Lu-177m content	Long-lived isomer within limits Lu-177 preparations; matters for waste handling	Gamma spectrometer

Setting up quality control?We can help you scope the equipment needed to release a given tracer.

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