Tracers / [18F]AlF-OncoFAP-NODAGA
[18F]AlF-OncoFAP-NODAGA
Also written as [18F]AlF-OncoFAP-NODAGA; [F-18]AlF-OncoFAP-NODAGA
- Radionuclide
- F-18 t½ 109.7 min
- Modality
- PET
- Production route
- Cyclotron liquid target
- Stage
- Research
- Syntheses indexed
- 0
What it is
- Compound class
- Small molecule chelate
- Target / mechanism
- FAP PMID 34957527 / DOI 10.1007/s00259-021-05653-0
- Clinical application
- —
- Theranostic pair
- <a href="/tracers/lu177-oncofap-dotaga/">lu177-oncofap-dotaga</a>
Regulatory status
- FDA
- No Drugs@FDA / openFDA drug registry — no approved application found; search: https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=BasicSearch.process&searchTerm=OncoFAP
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
No synthesis has been parsed for this agent yet.
Precursor
- Common precursor
- NODAGA-OncoFAP conjugate (from OncoFAP-COOH) PMID 36015106 / DOI 10.3390/ph15080958
- Suppliers seen in the literature
- —
- Typical final purification
- HPLC
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Get in touchQuality control Preliminary — inferred from compound class
- Ph. Eur. monograph
- —
- USP monograph
- —
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); receptor ligand with a saturable target -> molar activity (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [18F]AlF-OncoFAP-NODAGA.
Get in touchNotes
Aluminium fluoride chelation route.