By indication / Fibroblast activation / tumour stroma
Fibroblast activation / tumour stroma
14 imaging agents and 22 therapeutic agents reported for this indication. Stage reflects how far each has been taken, not what is available in any given country.
Imaging
| Agent | Isotope | Stage | Syntheses |
|---|---|---|---|
| [68Ga]Ga-FAPI-46 paired with [177Lu]Lu-FAPI-46 | Ga-68 | Clinical research | 77 |
| [68Ga]Ga-FAPI-04 paired with [177Lu]Lu-FAPI-04 | Ga-68 | — | 47 |
| [68Ga]Ga-FAPI paired with [177Lu]Lu-FAPI | Ga-68 | pilot clinical study | 25 |
| [18F]FAPI-74 | F-18 | — | 11 |
| [18F]AlF-FAPI-74 | F-18 | — | 10 |
| [18F]AlF-NOTA-FAPI-04 | F-18 | — | 7 |
| [68Ga]Ga-OncoFAP-DOTAGA paired with [177Lu]Lu-OncoFAP-DOTAGA | Ga-68 | Research | 4 |
| [18F]AlF-OncoFAP-NODAGA paired with [177Lu]Lu-OncoFAP-DOTAGA | F-18 | Research | |
| [18F]AlF-OncoFAP-NOTA paired with [177Lu]Lu-OncoFAP-DOTAGA | F-18 | Research | |
| [68Ga]Ga-OncoFAP-NODAGA | Ga-68 | Research | |
| [68Ga]Ga-OncoFAP-NOTA | Ga-68 | Research | |
| [18F]AlF-OncoFAP | F-18 | — | |
| [18F]FB-4AH29 | F-18 | preclinical | |
| [68Ga]Ga-FAPI-02 | Ga-68 | — |
Therapy
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