By indication / Fibroblast activation / tumour stroma

Fibroblast activation / tumour stroma

24 imaging agents and 15 therapeutic agents reported for this indication. Stage reflects how far each has been taken, not what is available in any given country.

Imaging

AgentIsotopeStageRuns
[68Ga]Ga-FAPI-46
paired with [177Lu]Lu-FAPI-46
Ga-68Clinical research41
[18F]AlF-FAPI-74F-18—8
[68Ga]Ga-FAPI-04
paired with [177Lu]Lu-FAPI-04
Ga-68—6
[68Ga]Ga-FAPI
paired with [177Lu]Lu-FAPI
Ga-68Clinical research5
[68Ga]Ga-OncoFAP-DOTAGAGa-68Research2
[18F]FAPI-74F-18—2
[18F]AlF-NOTA-FAPI-04F-18—1
[18F]FB-4AH29F-18Preclinical1
[68Ga]PEG2-COUGa-68Reported once1
[68Ga]PEG6-COUGa-68Reported once1
[89Zr]Nb159Zr-89Preclinical1
[89Zr]PEG-Nb159Zr-89Reported once1
[18F]AlF-H3RESCA-FAPIF-18Preclinical1
[111In]eFAP-6
paired with [177Lu]Lu-eFAP-6
In-111Preclinical1
[68Ga]DOTA-FD1
paired with [177Lu]Lu-DOTA-FD1
Ga-68Reported once1
[68Ga]DOTA-FD2
paired with [177Lu]Lu-DOTA-FD2
Ga-68Preclinical1
[68Ga]SB02055Ga-68Preclinical1
[18F]AlF-OncoFAP-NODAGAF-18Research
[18F]AlF-OncoFAP-NOTAF-18Research
[68Ga]Ga-OncoFAP-NODAGAGa-68Research
[68Ga]Ga-OncoFAP-NOTAGa-68Research
[18F]AlF-OncoFAPF-18—
[68Ga]Ga-FAPI-02Ga-68—
[68Ga]Ga-OncoFAP
paired with [177Lu]Lu-OncoFAP
Ga-68Clinical research

Therapy

AgentIsotopeStageRuns
[177Lu]Lu-FAPI-2286
paired with [64Cu]Cu-FAPI-2286
Lu-177—2
[212Pb]Pb-FAPI-46
paired with [68Ga]Ga-FAPI-46
Pb-212—1
[225Ac]Ac-DOTA-4AH29Ac-225Preclinical1
[177Lu]Lu-CHX-A''-DTPA-F8Lu-177Reported once1
[177Lu]Lu-PEG-Nb159
paired with [89Zr]PEG-Nb159
Lu-177Preclinical1
[225Ac]Ac-DOTA-PKU525Ac-225Reported once1
[177Lu]Lu-DOTA-PEG7-tetrazineLu-177Preclinical1
[177Lu]Lu-eFAP-6
paired with [111In]eFAP-6
Lu-177Preclinical1
[225Ac]Ac-FAPI-04
paired with [68Ga]Ga-FAPI-04
Ac-225Preclinical
[177Lu]Lu-DOTA-FAPI-04Lu-177Preclinical
[177Lu]Lu-DOTA-2P(FAPI)2Lu-177Preclinical
[177Lu]Lu-DOTA-NI-FAPI-04Lu-177Preclinical
[177Lu]Lu-177-OncoFAP-23Lu-177Preclinical
[111In]DOTAGA-FAP-2286In-111Reported once
[225Ac]Ac-DOTAGA-FAP-2286-ALBAc-225Reported once

Other entries

AgentIsotopeStageRuns
[68Ga]Ga-DATA5m.SA.FAPiGa-68Clinical research1

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