Tracer library / [177Lu]Lu-OncoFAP

Structure of OncoFAP (unlabelled parent compound, from PubChem) — Unlabelled parent compoundPubChem CID 156600097

[177Lu]Lu-OncoFAP

Also written as OncoFAP; Lu-177-OncoFAP

Radionuclide: Lu-177 t½ 9584.6 min
Modality: Therapy
Production route: —
Stage: Preclinical
Syntheses indexed: 0

Pan-cancer / multiple tumour types FAP-directed radioligand therapy

What it is

Compound class: FAP-targeted small organic radioligand (quinoline-based FAP inhibitor)
Target / mechanism: Fibroblast activation protein (FAP) PMID 36015106
Clinical application: Patients with FAP-positive solid tumors, for radioligand therapy PMID 39266289
Theranostic pair: [68Ga]Ga-OncoFAP

Published syntheses

No synthesis has been parsed for this agent yet.

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Notes

Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 2 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Diagnostic pair signal at discovery: YES - Ga-68.