By indication / FAP-directed radioligand therapy
FAP-directed radioligand therapy
3 imaging agents and 16 therapeutic agents reported for this indication. Stage reflects how far each has been taken, not what is available in any given country.
Imaging
| Agent | Isotope | Stage | Runs |
|---|---|---|---|
| [68Ga]Ga-FAPI paired with [177Lu]Lu-FAPI | Ga-68 | Clinical research | 5 |
| [68Ga]Ga-FAP-2286 paired with [177Lu]Lu-FAP-2286 | Ga-68 | — | 2 |
| [68Ga]Ga-FAPI-74 | Ga-68 | — | 1 |
Therapy
| Agent | Isotope | Stage | Runs |
|---|---|---|---|
| [177Lu]Lu-FAPI-46 paired with [68Ga]Ga-FAPI-46 | Lu-177 | Preclinical | 8 |
| [177Lu]Lu-FAPI paired with [68Ga]Ga-FAPI | Lu-177 | — | 5 |
| [177Lu]Lu-FAPI-2286 paired with [64Cu]Cu-FAPI-2286 | Lu-177 | — | 2 |
| [177Lu]Lu-DOTA-4AH29 | Lu-177 | Preclinical | 2 |
| [90Y]Y-FAPI-46 paired with [68Ga]Ga-FAPI-46 | Y-90 | Clinical research | 1 |
| [177Lu]Lu-FAP-2286 paired with [68Ga]Ga-FAP-2286 | Lu-177 | Clinical research | 1 |
| [211At]At-211-APBA-FAPI | At-211 | Preclinical | 1 |
| [177Lu]Lu-DOTA-FD1 paired with [68Ga]DOTA-FD1 | Lu-177 | Reported once | 1 |
| [177Lu]Lu-DOTA-FD2 paired with [68Ga]DOTA-FD2 | Lu-177 | Reported once | 1 |
| [177Lu]Lu-DOTA-FD3 paired with [68Ga]DOTA-FD3 | Lu-177 | Reported once | 1 |
| [177Lu]Lu-OncoFAP-DOTAGA paired with [68Ga]Ga-OncoFAP-DOTAGA | Lu-177 | Research | |
| [90Y]Y-FAPI paired with [68Ga]Ga-FAPI | Y-90 | Clinical research | |
| [225Ac]Ac-FAPI-46 paired with [68Ga]Ga-FAPI-46 | Ac-225 | Preclinical | |
| [177Lu]Lu-OncoFAP paired with [68Ga]Ga-OncoFAP | Lu-177 | Preclinical | |
| [177Lu]Lu-177-OncoFAP-23 | Lu-177 | Preclinical | |
| [177Lu]Lu-Evans | Lu-177 | Clinical research |
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