Tracers / [90Y]Y-FAPI

[90Y]Y-FAPI

Also written as [90Y]FAPI; [Y-90]FAPI; FAPI

Radionuclide: Y-90 t½ 3843 min
Modality: Therapy
Production route: —
Stage: —
Syntheses indexed: 1

What it is

Compound class: FAP inhibitor (FAPI) radiotracer
Target / mechanism: Fibroblast activation protein (FAP) expressed on cancer-associated fibroblasts (CAFs) PMID 41599688
Clinical application: —
Theranostic pair: <a href="/tracers/ga68-fapi/">ga68-fapi</a>

Regulatory status

FDA: —
EMA (centralised): —
Other approvals: —
Brand names: —

Clinical use

Typical injected activity: —
Uptake time: —

Reported in the literature. Not a dosing recommendation.

Published syntheses

Module	Cassette	Purification	Yield %	RCP %	Precursor / supplier	Source
—	—	—	—	—	—	41599688 2026 Pharmaceuticals (Basel)

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Quality control Preliminary — inferred from compound class

Ph. Eur. monograph: —
USP monograph: —

AppearancepHRCP HPLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrityOsmolalityMolar activityMetal impurities

How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); radiometal tracer -> metal impurities (rule); therapeutic radiopharmaceutical -> osmolality (rule); receptor ligand with a saturable target -> molar activity (rule)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 4 article(s) with Y-90.