Tracer library / [68Ga]Ga-OncoFAP
Structure of OncoFAP (unlabelled parent compound, from PubChem)
Unlabelled parent compoundPubChem CID 156600097

[68Ga]Ga-OncoFAP

Also written as [68Ga]Ga-OncoFAP; [Ga-68]Ga-OncoFAP; Ga-68 OncoFAP; Ga-68-OncoFAP; OncoFAP
Radionuclide
Ga-68 t½ 67.71 min
Modality
PET
Production route
—
Stage
Clinical research
Syntheses indexed
0

What it is

Compound class
FAP inhibitor (FAP-targeted small molecule ligand)
Target / mechanism
Fibroblast activation protein (FAP) PMID 36015106
Clinical application
Solid malignancies imaged by PET; FAP-positive solid tumors targeted therapy PMID 36015106
Theranostic pair
[177Lu]Lu-OncoFAP

Published syntheses

No synthesis has been parsed for this agent yet.

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph
not verified No Ph. Eur. check is recorded for this entry.
USP monograph
not verified No USP check is recorded for this entry.
AppearancepHRCP HPLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrityMetal impuritiesGe-68 breakthrough
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); radiometal tracer -> metal impurities (rule); Ga-68, generator production assumed (no synthesis data found) -> Ge-68 breakthrough (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 3 article(s) with Ga-68. Also seen with Lu-177[1] (too few articles for own row). Stage set/updated at stage 39 from PMID 36015106: 'OncoFAP has been recently discovered and clinically validated for PET imaging procedures in patients with solid malignancies.'.
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