By indication / Pan-cancer / multiple tumour types

Pan-cancer / multiple tumour types

12 imaging agents and 9 therapeutic agents reported for this indication. Stage reflects how far each has been taken, not what is available in any given country.

Imaging

AgentIsotopeStageSyntheses
[18F]FDGF-18Approved164
[68Ga]Ga-FAPI-46
paired with [177Lu]Lu-FAPI-46
Ga-68Clinical research77
[68Ga]Ga-FAPI-04
paired with [177Lu]Lu-FAPI-04
Ga-6847
[18F]FAPI-74F-1811
[18F]FSPGF-18Clinical research9
[68Ga]Ga-OncoFAP-DOTAGAGa-68Research4
[18F]FTYRF-18Research3
[18F]fluoroacetateF-182
10-[11C]methoxy-20(S)-camptothecinC-11preclinical1
[11C]YM155C-111
[18F]AlF-OncoFAPF-18
[18F]L-GlutamicF-18investigational

Therapy

AgentIsotopeStageSyntheses
[90Y]Y-pentixatherY-909
[177Lu]Lu-NeoBLu-177phase I/IIa clinical trial (first-in-human)2
[225Ac]Ac-DOTA-hu3F8Ac-225preclinical2
[90Y]Y-90-FF-21101Y-90phase I/II clinical trial2
[177Lu]Lu-AKIR001Lu-177phase 1 clinical trial2
[89Zr]PEG-Nb159Zr-89Reported once1
[68Ga]DOTA-FD1
paired with [177Lu]Lu-DOTA-FD1
Ga-68Reported once1
[177Lu]Lu-DOTA-MI-exendin-4Lu-177Reported once1
[177Lu]Lu-OncoFAP
paired with [68Ga]Ga-OncoFAP
Lu-177preclinical

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