Tracer library / [18F]Talazoparib

[18F]Talazoparib

Also written as [18F]Talazoparib
Radionuclide
F-18
Modality
—
Production route
—
Stage
Preclinical
Syntheses indexed
1
Pan-cancer / multiple tumour types

What it is

Compound class
PARP inhibitor (talazoparib derivative), radiolabeled small molecule
Target / mechanism
Poly(ADP-ribose) polymerase (PARP) PMID 34672571
Clinical application
Detection and stratification of various PARP-expressing cancers PMID 34672571
Theranostic pair
—

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
——HPLC13 ± 3.4%——34672571
2021 J Med Chem

Need this precursor?We can point you to suppliers for [18F]Talazoparib, or handle the enquiry for you.

Get in touch

Notes

Added at stage 39 (2026-09-27) from a reverse search of the PubMed corpus's own unattached articles (articles that named a real compound not yet in this reference): 2 article(s) found under this name, not yet individually researched. Target/mechanism, clinical application, indications, approval, modality, stage and production route are intentionally left empty. PMIDs: 34672571, 42257398. Stage set/updated at stage 39 from PMID 34672571: '(8S,9R)-[18F]Talazoparib demonstrated PARP binding in HCC1937 cells in vitro and showed an excellent tumor-to-blood ratio in xenograft-bearing mice (10.2 ± 1.5).'.