Tracer library / [68Ga]Ga-DATA5m.SA.FAPi

[68Ga]Ga-DATA5m.SA.FAPi

Also written as [68Ga]Ga-DATA5m.SA.FAPi
Radionuclide
Ga-68
Modality
—
Production route
—
Stage
Clinical research
Syntheses indexed
1
Fibrosis (non-oncologic)Head and neck cancerHepatobiliary and pancreatic cancerLung cancerPan-cancer / multiple tumour typesProstate cancerSarcoma (soft tissue and bone)Fibroblast activation / tumour stroma

What it is

Compound class
FAP inhibitor (FAPI) radiotracer with DATA.SA hybrid chelate and squaric acid linker
Target / mechanism
Fibroblast activation protein (FAP) on cancer-associated fibroblasts (CAF) / disease-associated fibroblasts (DAF) PMID 36015148
Clinical application
Detection of cancer-associated fibroblasts in multiple carcinomas (NSCLC, liposarcoma, parotid tumors, prostate cancer, pancreas adenocarcinoma) and their metastases PMID 36015148
Theranostic pair
—

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
Manual synthesis—HPLC—98.5 ± 1.4%DATA5m.SA.FAPi41599636
2025 Pharmaceuticals (Basel)
detailed procedures for the manual radiosynthesis are provided by Weissenböck et al.

Clinical literature

Clinical studies in the indexed corpus, ordered by design (multicentre, prospective, retrospective, others, case reports last) and then by year. Titles and links only, as published; this is not a summary of the evidence.

  1. From Automated Synthesis to In Vivo Application in Multiple Types of Cancer-Clinical Results with [68Ga]Ga-DATA5m.SA.FAPi.
    2022 · Pharmaceuticals (Basel) · Clinical study

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Notes

Added at stage 39 (2026-09-27) from a reverse search of the PubMed corpus's own unattached articles (articles that named a real compound not yet in this reference): 2 article(s) found under this name, not yet individually researched. Target/mechanism, clinical application, indications, approval, modality, stage and production route are intentionally left empty. PMIDs: 36015148, 41599636. Stage set/updated at stage 39 from PMID 36015148: 'From Automated Synthesis to In Vivo Application in Multiple Types of Cancer-Clinical Results with [68Ga]Ga-DATA5m.SA.FAPi.'.