Tracer library / 10-[11C]methoxy-20(S)-camptothecin

10-[11C]methoxy-20(S)-camptothecin

Also written as 10-[11C]methoxy-20(S)-camptothecin

Radionuclide: C-11 t½ 20.36 min
Modality: PET
Production route: —
Stage: Preclinical
Syntheses indexed: 1

Pan-cancer / multiple tumour types Dosimetry and biodistribution studies

What it is

Compound class: carbon-11-labeled camptothecin derivative
Target / mechanism: Topoisomerase I PMID 15993064
Clinical application: cancers PMID 15993064
Theranostic pair: —

Published syntheses

Module	Cassette	Purification	Yield %	RCP %	Precursor / supplier	Source
—	—	—	30%-50%	>96%	—	22885394 2012 Appl Radiat Isot

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph: not verified No Ph. Eur. check is recorded for this entry.
USP monograph: not verified No USP check is recorded for this entry.

AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity

How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 1 article(s) with C-11.