Tracers / [11C]CP31398

[11C]CP31398

Also written as [11C]CP31398; [C-11]CP31398
Radionuclide
C-11 t½ 20.36 min
Modality
PET
Production route
Stage
preclinical study
Syntheses indexed
1

What it is

Compound class
Target / mechanism
Clinical application
Theranostic pair

Regulatory status

FDA
EMA (centralised)
Other approvals
Brand names

Clinical use

Typical injected activity
Uptake time

Reported in the literature. Not a dosing recommendation.

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
TRACERlab FX C Pro
GE HealthCare
HPLC40 ± 13
yes
>99%phenol precursor 241696278
2026 ACS Omega
the whole radiochemical process was automated using the TRACERlab FX C Pro module and the optimized conditions — afforded ready-to-inject [11C]CP31398 (0.6–1.6 GBq) in 40 ± 13% (n = 6) RCY within 40 min (nondecay corrected activity yield of 10 ± 3%)

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Quality control Preliminary — inferred from compound class

Ph. Eur. monograph
USP monograph
AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 1 article(s) with C-11. Stage set/updated at stage 23 from PMID 41696278: 'Binding experiments performed with [18F]FG-CP31398 on HEK-293T cells transfected with a green fluorescent protein-p53 wild-type plasmid'.