Tracer library / [188Re]Re-188-DTPA-deoxyglucose
[188Re]Re-188-DTPA-deoxyglucose
Also written as Re-188-DTPA-deoxyglucose
- Radionuclide
- Re-188 t½ 1020 min
- Modality
- Therapy
- Production route
- —
- Stage
- —
- Syntheses indexed
- 2
What it is
- Compound class
- DTPA-conjugated deoxyglucose (glucose analog chelated with DTPA)
- Target / mechanism
- —
- Clinical application
- Breast cancer (MCF-7 tumor model), potential cancer radiopharmaceutical for tumor diagnosis and radiotherapy PMID 20173156
- Theranostic pair
- —
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| — | — | — | — | 95.0% | DTPA-DG | 20173156 2010 AJR Am J Roentgenol |
| Manual synthesis n/a | — | — | — | 95.0% | DTPA-DG | 17651046 2007 Cancer Biother Radiopharm Labeling of DTPA-DG with (188)Re was performed in the presence of stannous ion and sodium D-gluconate at a pH of 5.5 with 3 hours of incubation at 37 degrees C. |
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Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 2 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Compound class inferred from precursor name (not stated outright) -- PMID 20173156: 'diethylenetriamine pentaacetic acid-deoxyglucose (DTPA-DG)'.