Tracer library / [11C]YM155
Structure of YM155 (unlabelled parent compound, from PubChem)
Unlabelled parent compoundPubChem CID 11178236

[11C]YM155

Also written as [11C]YM155; [C-11]YM155
Radionuclide
C-11 t½ 20.36 min
Modality
PET
Production route
—
Stage
—
Syntheses indexed
1
LymphomaPan-cancer / multiple tumour typesProstate cancerApoptosis and early treatment response

What it is

Compound class
survivin suppressant small molecule (imidazolium-based compound)
Target / mechanism
Survivin PMID 23141550
Clinical application
Patients with various cancers (including non-Hodgkin lymphoma, lung cancer, and breast cancer) undergoing YM155 treatment, for prediction of tumor response PMID 30041149
Theranostic pair
—

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
———16-22%
decay-corrected
>99%ethanolamine-alkolate23141550
2013 Nucl Med Biol

Need this precursor?We can point you to suppliers for [11C]YM155, or handle the enquiry for you.

Get in touch

Quality control Preliminary - inferred from compound class

Ph. Eur. monograph
not verified No Ph. Eur. check is recorded for this entry.
USP monograph
not verified No USP check is recorded for this entry.
AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

Setting up quality control?We can help you scope the equipment needed to release [11C]YM155.

Get in touch

Notes

Added from reverse module search (stage 6); 1 article(s) with C-11.
Ask a question