Tracer library / [68Ga]DOTA-FD1
[68Ga]DOTA-FD1
Also written as [Ga-68]Ga-DOTA-FD1
- Radionuclide
- Ga-68 t½ 67.71 min
- Modality
- PET
- Production route
- —
- Stage
- Reported once
- Syntheses indexed
- 1
What it is
- Compound class
- FAP-targeted peptide, DOTA-conjugated
- Target / mechanism
- Fibroblast activation protein (FAP) PMID 38706713
- Clinical application
- PET imaging of FAP dynamics in primary and metastatic tumors PMID 38706713
- Theranostic pair
- [177Lu]Lu-DOTA-FD1
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| Manual synthesis | — | none | — | 99% | FD1 | 38706713 2023 Research (Wash D C) This mixture was added to 400 μl of 68GaCl3 solution (containing 37 MBq) in 0.1 M HCl, with pH adjusted to 4.0 using 0.1 M NH4OAC. The mixture was incubated at 100 °C for 10 min without any additional purification steps. |
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Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 38706713. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. | Stage 30 (2026-09-18): Modality was 'Therapy' -- a bucket value given to every agent found by the therapy-oriented bulk search (stages 21-22), not a source statement. Corrected to PET: Ga-68 is a positron emitter used only for PET imaging. Linked articles: PMID 38706713.