Tracers / [68Ga]Ga-OncoFAP-NOTA
[68Ga]Ga-OncoFAP-NOTA
Also written as [68Ga]Ga-OncoFAP-NOTA; [Ga-68]Ga-OncoFAP-NOTA
- Radionuclide
- Ga-68 t½ 67.7 min
- Modality
- PET
- Production route
- Generator
- Stage
- Research
- Syntheses indexed
- 0
What it is
- Compound class
- Small molecule chelate
- Target / mechanism
- FAP PMID 34957527 / DOI 10.1007/s00259-021-05653-0
- Clinical application
- —
- Theranostic pair
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Regulatory status
- FDA
- No Drugs@FDA / openFDA drug registry — no approved application found; search: https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=BasicSearch.process&searchTerm=OncoFAP
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
No synthesis has been parsed for this agent yet.
Precursor
- Common precursor
- NOTA-OncoFAP conjugate (from OncoFAP-COOH) PMID 36015106 / DOI 10.3390/ph15080958
- Suppliers seen in the literature
- —
- Typical final purification
- SPE
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Get in touchQuality control Preliminary — inferred from compound class
- Ph. Eur. monograph
- —
- USP monograph
- —
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); radiometal tracer -> metal impurities (rule); Ga-68, generator production assumed (no synthesis data found) -> Ge-68 breakthrough (preliminary); receptor ligand with a saturable target -> molar activity (rule)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
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