Preclinical only, no clinical indication yet

By indication / Preclinical only, no clinical indication yet

93 imaging agents and 99 therapeutic agents reported for this indication. Stage reflects how far each has been taken, not what is available in any given country.

Imaging

Agent	Isotope	Stage	Runs
[68Ga]Ga-BPAMD paired with [161Tb]Tb-BPAMD	Ga-68	Clinical research	5
[68Ga]Ga-TRAP-(RGD)3	Ga-68	—	3
[11C]L-glutamine	C-11	—	2
[18F]AlF-3p-C-NETA-TATE	F-18	Preclinical	2
[18F]fluoroacetate	F-18	—	2
[18F]F-PSMA-617-NODA	F-18	—	2
[18F]F-PSMA-617-RESCA	F-18	—	2
[89Zr]DFO-F8	Zr-89	Reported once	2
[68Ga]DOTA-A1-His	Ga-68	Preclinical	2
[68Ga]AAZTA-FAPI-46	Ga-68	Preclinical	2
[18F]BPAM121	F-18	Research	1
[18F]TTCO-IL2	F-18	Research	1
[11C]PK68	C-11	Preclinical	1
[11C]PS13	C-11	Clinical research	1
[18F]ADPM06	F-18	Preclinical	1
[18F]AG-120	F-18	Preclinical	1
[18F]AQ28A	F-18	Preclinical	1
[18F]EKZ-001	F-18	Preclinical	1
[18F]FBAM	F-18	Preclinical	1
[18F]FBEM-Cys-H4	F-18	Preclinical	1
[18F]FCPPC	F-18	—	1
[18F]FG-CP31398	F-18	Preclinical	1
[18F]FPG-IL4	F-18	Preclinical	1
[18F]JMV5763	F-18	—	1
[18F]mBPET-1	F-18	—	1
[18F]MEL050	F-18	Clinical research	1
[18F]NS10743	F-18	Preclinical	1
[68Ga]Ga-DOTA-r-a-ABA-CPCR4 paired with [177Lu]Lu-DOTA-r-a-ABA-CPCR4	Ga-68	Preclinical	1
[68Ga]Ga-NOTA-BBN2	Ga-68	Preclinical	1
[89Zr]Zr-TROP2	Zr-89	Preclinical	1
[89Zr]DFO-Per-F(ab')2	Zr-89	Preclinical	1
[68Ga]PEG2-COU	Ga-68	Reported once	1
[68Ga]PEG6-COU	Ga-68	Reported once	1
[99mTc]N4-CCK-66	Tc-99m	Preclinical	1
[99mTc]N4-CCK-100	Tc-99m	Preclinical	1
[99mTc]N4-CCK-104	Tc-99m	Preclinical	1
[67Ga]Comb-2	Ga-67	Preclinical	1
[111In]DOTA-MSC3 paired with [225Ac]Ac-DOTA-MSC3	In-111	Preclinical	1
[68Ga]DOTA-KiSS-34 paired with [177Lu]Lu-DOTA-KiSS-34	Ga-68	Reported once	1
[68Ga]PKB2	Ga-68	Reported once	1
[64Cu]SarAr-PEG10-Tz paired with [67Cu]Cu-SarAr-PEG10-Tz	Cu-64	Preclinical	1
[89Zr]DFO-11E10C11	Zr-89	Preclinical	1
[89Zr]Nb159	Zr-89	Preclinical	1
[89Zr]PEG-Nb159 paired with [177Lu]Lu-PEG-Nb159	Zr-89	Reported once	1
[86Y]pepa-pic2-C-Hex-KuE	Y-86	Reported once	1
[86Y]pepa-pic2	Y-86	Preclinical	1
[68Ga]NOTA-A1-His	Ga-68	Preclinical	1
[18F]AlF-NOTA-iPD-L1	F-18	Preclinical	1
[111In]DOTA-TRK-950 paired with [177Lu]Lu-DOTA-TRK-950	In-111	Reported once	1
[18F]AlF-H3RESCA-FAPI	F-18	Preclinical	1
[68Ga]LW02060 paired with [177Lu]Lu-LW02060	Ga-68	Reported once	1
[68Ga]LW02080 paired with [177Lu]Lu-LW02080	Ga-68	Reported once	1
[68Ga]TATE-46	Ga-68	Preclinical	1
[68Ga]BCY18469	Ga-68	Preclinical	1
[111In]BCY18469	In-111	Preclinical	1
[111In]eFAP-6 paired with [177Lu]Lu-eFAP-6	In-111	Preclinical	1
[68Ga]DOTA-FD2 paired with [177Lu]Lu-DOTA-FD2	Ga-68	Preclinical	1
[68Ga]DOTA-FD3 paired with [177Lu]Lu-DOTA-FD3	Ga-68	Preclinical	1
[89Zr]DFO-NY003/	Zr-89	Preclinical	1
[68Ga]HTK03177	Ga-68	Preclinical	1
[203Pb]eSOMA-01	Pb-203	Reported once	1
[18F]AlF-3p-C-NETA-ePSMA-16	F-18	Preclinical	1
[68Ga]SB02055	Ga-68	Preclinical	1
[68Ga]SB04028	Ga-68	Preclinical	1
[68Ga]NOTA-MI-exendin-4	Ga-68	Preclinical	1
[99mTc]Tc(CO)3-NOTA-PEG2Nle-CycMSHhex	Tc-99m	Reported once	1
[99mTc]Tc(CO)3-NOTA-AocNle-CycMSHhex	Tc-99m	Reported once	1
[68Ga]NOTA-C2	Ga-68	Reported once	1
[68Ga]NOTA-ABDC2	Ga-68	Preclinical	1
[68Ga]TacBOMB2	Ga-68	Reported once	1
[68Ga]TacBOMB3	Ga-68	Reported once	1
[111In]DO3A-BODIPY-Tz-TCO-trastuzumab	In-111	Preclinical	1
[99mTc]Tc(CO)3-GRGDHV	Tc-99m	Preclinical	1
[18F]AlF-NOTA-DV1-k-(DV3)	F-18	Reported once	1
[124I]PN67 paired with [131I]PN67	I-124	Reported once	1
[68Ga]177-AAZTA5-PSMA-617 paired with [177Lu]Lu-177-AAZTA5-PSMA-617	Ga-68	Preclinical	1
[44Sc]177-AAZTA5-PSMA-617	Sc-44	Preclinical	1
[68Ga]DOTA-r-a-ABA-iodoCPCR4 paired with [177Lu]Lu-DOTA-r-a-ABA-iodoCPCR4	Ga-68	Preclinical	1
[64Cu]Pep-1L paired with [225Ac]Ac-Pep-1L	Cu-64	Preclinical	1
[18F]FRPG	F-18	Research
[18F]AlF-OncoFAP-NODAGA paired with [177Lu]Lu-OncoFAP-DOTAGA	F-18	Research
[18F]AlF-OncoFAP-NOTA paired with [177Lu]Lu-OncoFAP-DOTAGA	F-18	Research
[68Ga]Ga-OncoFAP-NODAGA	Ga-68	Research
[68Ga]Ga-OncoFAP-NOTA	Ga-68	Research
[18F]SqFLT	F-18	Research
[18F]FSO3-PSMA	F-18	Research
[18F]ef5	F-18	—
[18F]FB-S100s	F-18	Preclinical
6-[18F]fluoro-3-(pyridin-3-yl)-1H-indole	F-18	Preclinical
[68Ga]Ga-DOTA-AMBS-CPCR4	Ga-68	—
[111In]DOTAGA-FAP-2286-ALB paired with [225Ac]Ac-DOTAGA-FAP-2286-ALB	In-111	Preclinical
[68Ga]TacsBOMB3	Ga-68	Preclinical
[68Ga]TacsBOMB6	Ga-68	Reported once

Therapy

Agent	Isotope	Stage	Runs
[177Lu]Lu-RM2 paired with [68Ga]Ga-RM2	Lu-177	—	7
[177Lu]Lu-FAPI paired with [68Ga]Ga-FAPI	Lu-177	—	5
[161Tb]Tb-DOTATATE paired with [68Ga]Ga-DOTATATE	Tb-161	Preclinical	3
[177Lu]Lu-DOTA-JR11	Lu-177	Clinical research	3
[177Lu]Lu-FAPI-04 paired with [68Ga]Ga-FAPI-04	Lu-177	Clinical research	2
[177Lu]Lu-FAPI-2286 paired with [64Cu]Cu-FAPI-2286	Lu-177	—	2
[211At]At-astatobenzoate	At-211	Clinical research	2
[177Lu]Lu-DOTA-4AH29	Lu-177	Preclinical	2
[90Y]Y-90-ITGA6B4	Y-90	—	2
[212Pb]Pb-TCMC-chOI-1	Pb-212	Preclinical	2
[111In]pb12	In-111	Preclinical	2
[177Lu]Lu-DOTA-r-a-ABA-iodoCPCR4 paired with [68Ga]DOTA-r-a-ABA-iodoCPCR4	Lu-177	Preclinical	1
[177Lu]Lu-DOTA-rhCCK-18	Lu-177	—	1
[161Tb]Tb-3p-C-NETA paired with [68Ga]Ga-3p-C-NETA	Tb-161	Preclinical	1
[47Sc]Sc-PSMA-617 paired with [111In]In-PSMA-617	Sc-47	Preclinical	1
[161Tb]Tb-RM2 paired with [68Ga]Ga-RM2	Tb-161	Preclinical	1
[212Pb]Pb-FAPI-46 paired with [68Ga]Ga-FAPI-46	Pb-212	—	1
[47Sc]Sc-DOTANOC paired with [68Ga]Ga-DOTANOC	Sc-47	Preclinical	1
[90Y]Y-90-NM600	Y-90	Preclinical	1
[161Tb]Tb-AMTG	Tb-161	Preclinical	1
[225Ac]Ac-DOTA-4AH29	Ac-225	Preclinical	1
[177Lu]Lu-DOTA-exendin-4 paired with [68Ga]Ga-DOTA-exendin-4	Lu-177	Preclinical	1
[131I]I-GMIB-4AH29	I-131	Preclinical	1
[177Lu]Lu-satoreotide	Lu-177	Clinical research	1
[177Lu]Lu-DOTA-(DGlu)6-Ala-Tyr-Gly-Trp-Nle-Asp-Phe-NH2	Lu-177	—	1
[188Re]Re-188-HYNIC-BBN	Re-188	Preclinical	1
[177Lu]Lu-Rituximab	Lu-177	Preclinical	1
[177Lu]Lu-DOTA-r-a-ABA-CPCR4 paired with [68Ga]Ga-DOTA-r-a-ABA-CPCR4	Lu-177	—	1
[177Lu]Lu-BL02	Lu-177	Preclinical	1
[131I]I-Tyr-d-peptide-PEG11-Tz	I-131	Reported once	1
[131I]I-BNF03	I-131	Reported once	1
[131I]I-WS03	I-131	Preclinical	1
[177Lu]Lu-Comb-2	Lu-177	Preclinical	1
[177Lu]Lu-DOTA-ABDB6	Lu-177	Reported once	1
[225Ac]Ac-DOTA-MSC3 paired with [111In]DOTA-MSC3	Ac-225	Preclinical	1
[177Lu]Lu-DOTA-KiSS-34 paired with [68Ga]DOTA-KiSS-34	Lu-177	Preclinical	1
[177Lu]Lu-BL34 paired with [68Ga]BL34	Lu-177	Preclinical	1
[177Lu]Lu-DOTA-11E10C11	Lu-177	Reported once	1
[177Lu]Lu-DOTA-GA4	Lu-177	Preclinical	1
[177Lu]Lu-DOTA-GA13	Lu-177	Reported once	1
[177Lu]Lu-PEG-Nb159 paired with [89Zr]PEG-Nb159	Lu-177	Preclinical	1
[225Ac]Ac-3p-C-DEPA-NO2	Ac-225	Preclinical	1
[225Ac]Ac-3p-C-DEPA-TFP-PEG4-trastuzumab	Ac-225	Preclinical	1
[177Lu]Lu-pepa-pic2-C-Hex-KuE	Lu-177	Reported once	1
[161Tb]Tb-pepa-pic2-C-Hex-KuE	Tb-161	Preclinical	1
[177Lu]Lu-DOTA-iPD-L1	Lu-177	Preclinical	1
[177Lu]Lu-DOTA-TRK-950 paired with [111In]DOTA-TRK-950	Lu-177	Preclinical	1
[177Lu]Lu-cAC10	Lu-177	Preclinical	1
[177Lu]Lu-DOTA-AE105	Lu-177	Preclinical	1
[177Lu]Lu-LW01110	Lu-177	Preclinical	1
[177Lu]Lu-LW01142	Lu-177	Reported once	1
[177Lu]Lu-LW02060 paired with [68Ga]LW02060	Lu-177	Reported once	1
[177Lu]Lu-LW02080 paired with [68Ga]LW02080	Lu-177	Preclinical	1
[225Ac]Ac-Macropa-N4MU01	Ac-225	Reported once	1
[225Ac]Ac-DOTA-PKU525	Ac-225	Reported once	1
[131I]I-ERIC1	I-131	Preclinical	1
[212Pb]Pb-DOTAM-GRPR1	Pb-212	Preclinical	1
[177Lu]Lu-DOTA-PEG7-tetrazine	Lu-177	Preclinical	1
[177Lu]Lu-BCY18469	Lu-177	Preclinical	1
[177Lu]Lu-eFAP-6 paired with [111In]eFAP-6	Lu-177	Preclinical	1
[177Lu]Lu-DOTA-POL3026	Lu-177	Reported once	1
[177Lu]Lu-DOTA-FD3 paired with [68Ga]DOTA-FD3	Lu-177	Reported once	1
[177Lu]Lu-PEG-(DOTA)1	Lu-177	Preclinical	1
[177Lu]Lu-PEG-(DOTA)1(ACUPA)3	Lu-177	Reported once	1
[111In]AT2S	In-111	Preclinical	1
[177Lu]Lu-DTPA-NY003	Lu-177	Preclinical	1
[212Pb]Pb-eSOMA-02	Pb-212	Reported once	1
[177Lu]Lu-3p-C-NETA-ePSMA-16	Lu-177	Preclinical	1
[213Bi]Bi-3p-C-NETA-ePSMA-16	Bi-213	Preclinical	1
[177Lu]Lu-DOTA-MI-exendin-4	Lu-177	Reported once	1
[177Lu]Lu-DOTA-ABDC2	Lu-177	Reported once	1
[125I]NaIO3	I-125	Reported once	1
[211At]At-NaAtO3	At-211	Preclinical	1
[123I]PARPi-01	I-123	Preclinical	1
[111In]BQ7859	In-111	Reported once	1
[131I]PN67 paired with [124I]PN67	I-131	Reported once	1
[131I]GV-620	I-131	Preclinical	1
[225Ac]Ac-hu5A10	Ac-225	Reported once	1
[131I]I-T-ZHP1	I-131	Reported once	1
[177Lu]Lu-177-AAZTA5-PSMA-617 paired with [68Ga]177-AAZTA5-PSMA-617	Lu-177	Reported once	1
[177Lu]Lu-6R-RedFol-1	Lu-177	Reported once	1
[177Lu]Lu-6S-RedFol-1	Lu-177	Preclinical	1
[177Lu]Lu-OxFol-1	Lu-177	Reported once	1
[177Lu]Lu-DOTA-ST8950	Lu-177	Reported once	1
[131I]MEGMIB-5F7GGC	I-131	Reported once	1
[131I]PSMA-769	I-131	Reported once	1
[177Lu]Lu-OncoFAP-DOTAGA paired with [68Ga]Ga-OncoFAP-DOTAGA	Lu-177	Research
[169Er]Er-PSMA-617 paired with [111In]In-PSMA-617	Er-169	Preclinical
[131I]FAPI paired with [68Ga]Ga-FAPI	I-131	Preclinical
[177Lu]Lu-DOTA-FAPI-04	Lu-177	Preclinical
[188Re]Re-RC-160	Re-188	Preclinical
[67Cu]Cu-SARTATE paired with [64Cu]Cu-sartate	Cu-67	Preclinical
[177Lu]Lu-PSMA-617-treated	Lu-177	Clinical research
[225Ac]Ac-crown-TATE	Ac-225	—
[177Lu]Lu-DOTA-NI-FAPI-04	Lu-177	Preclinical
[211At]At-astatophenethylsuccinamate	At-211	Preclinical
[225Ac]Ac-Macropa-pertuzumab-PEG6-DM1	Ac-225	Preclinical
[111In]DOTAGA-FAP-2286	In-111	Reported once
[225Ac]Ac-DOTAGA-FAP-2286-ALB paired with [111In]DOTAGA-FAP-2286-ALB	Ac-225	Reported once

Other entries

Agent	Isotope	Stage	Runs
[125I]CPCR4.3	I-125	Preclinical	1
[177Lu]Lu-DOTA-cyclo-MG1	Lu-177	Preclinical	1
[177Lu]Lu-DOTA-cyclo-MG2	Lu-177	Preclinical	1
[177Lu]Lu-DOTA-Tz	Lu-177	Preclinical
[213Bi]Bi-2556	Bi-213	Preclinical
[188Re]Re-Liposome		Preclinical
[211At]At-(RGD)4	At-211	Preclinical
[140Nd]Nd-DOTA	Nd-140	Preclinical
[225Ac]Ac3+	Ac-225	Preclinical
[166Ho]Ho-TRITP	Ho-166	Preclinical

Have a question?Reagents, modules, introductions to manufacturers or to specialists in your region - tell us what you need.

Get in touch