Tracers / [177Lu]Lu-BL34
[177Lu]Lu-BL34
Also written as [Lu-177]Lu-BL34
- Radionuclide
- Lu-177 t½ 9584.6 min
- Modality
- Therapy
- Production route
- —
- Stage
- preclinical study
- Syntheses indexed
- 1
What it is
- Compound class
- CXCR4-targeting cyclic peptide with DOTA chelator
- Target / mechanism
- C-X-C chemokine receptor 4 (CXCR4) PMID 41611474
- Clinical application
- —
- Theranostic pair
- <a href="/tracers/ga68-bl34/">ga68-bl34</a>
Regulatory status
- FDA
- —
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| — | — | — | 41.8 ± 22.8% | >95% | BL34 (10) | 41611474 2026 J Nucl Med |
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Get in touchNotes
Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 41611474. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Stage set/updated at stage 23 from PMID 41611474: '[68Ga]Ga-BL34 and [177Lu]Lu-BL34 showed excellent imaging and therapeutic properties in preclinical studies and are promising candidates for clinical translation.'.