Tracer library / [68Ga]BL34

[68Ga]BL34

Also written as [Ga-68]Ga-BL34
Radionuclide
Ga-68 t½ 67.71 min
Modality
PET
Production route
—
Stage
Preclinical
Syntheses indexed
1

What it is

Compound class
CXCR4-targeting cyclic peptide with DOTA chelator
Target / mechanism
CXCR4 (C-X-C chemokine receptor 4) antagonist/binder PMID 41611474
Clinical application
Preclinical theranostic imaging and therapy of CXCR4-expressing mantle cell lymphoma model PMID 41611474
Theranostic pair
[177Lu]Lu-BL34

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
———73.5 ± 1.9%>99%BL34 (10)41611474
2026 J Nucl Med

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Notes

Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 41611474. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Stage set/updated at stage 23 from PMID 41611474: '[68Ga]Ga-BL34 and [177Lu]Lu-BL34 showed excellent imaging and therapeutic properties in preclinical studies and are promising candidates for clinical translation.'. | Stage 30 (2026-09-18): Modality was 'Therapy' -- a bucket value given to every agent found by the therapy-oriented bulk search (stages 21-22), not a source statement. Corrected to PET: Ga-68 is a positron emitter used only for PET imaging. Linked articles: PMID 41611474.
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