Tracers / [64Cu]Cu-sartate
[64Cu]Cu-sartate
Also written as Cu-64 SARTATE; SARTATE
- Radionuclide
- Cu-64 t½ 762 min
- Modality
- PET
- Production route
- —
- Stage
- first-in-human
- Syntheses indexed
- 4
What it is
- Compound class
- Sarcophagine-conjugated somatostatin analog peptide (SarTATE, MeCOSar-Tyr3-octreotate)
- Target / mechanism
- Somatostatin receptor (SSTR) binding via octreotate peptide PMID 30442752
- Clinical application
- PET/CT imaging of somatostatin receptor-positive neuroendocrine tumors, with potential for prospective dosimetry for PRRT PMID 30442752
- Theranostic pair
- <a href="/tracers/cu67-sartate/">cu67-sartate</a>
Regulatory status
- FDA
- —
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| — | — | — | — | — | — | 30442752 2019 J Nucl Med |
| Manual synthesis | — | — | — | — | SarTATE | 42201774 2026 Inorg Chem Copper-64 (46.25 MBq, 1.25 mCi) in 0.1 M HCl was neutralized with PBS and NaOH and combined with SarTATE |
| Kit-based preparation | — | — | — | — | — | 41754861 2026 Pharmaceuticals (Basel) [64Cu]Cu-SAR-TATE |
| — | — | — | — | — | — | 30442752 2019 J Nucl Med |
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Get in touchQuality control Derived from the published synthesis
- Ph. Eur. monograph
- —
- USP monograph
- —
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); radiometal tracer -> metal impurities (rule); receptor ligand with a saturable target -> molar activity (rule)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [64Cu]Cu-sartate.
Get in touchNotes
Added from reverse module search (stage 6); 1 article(s) with Cu-64. Also seen with Cu-67[1] (too few articles for own row). Stage set/updated at stage 23 from PMID 30442752: 'we have performed a first-time-in-humans trial of 64Cu-MeCOSar-Tyr3-octreotate (64Cu-SARTATE) to assess its safety and ability to localize disease at early and late imaging time-points'.