Tracer library / [67Cu]Cu-SARTATE
Structure of SARTATE (unlabelled parent compound, from PubChem)
Unlabelled parent compoundPubChem CID 137347535

[67Cu]Cu-SARTATE

Also written as [Cu-67]Cu-SARTATE; SarTATE
Radionuclide
Cu-67 t½ 3708 min
Modality
Therapy
Production route
—
Stage
Preclinical
Syntheses indexed
0

What it is

Compound class
CB-TE1A1P-PEG4-LLP2A (VLA-4-targeting peptidomimetic conjugated to CB-TE1A1P chelator)
Target / mechanism
VLA-4 (integrin α4β1) PMID 39911068
Clinical application
Neuroendocrine tumors (preclinical); unresectable multifocal meningioma (clinical) PMID 32414949
Theranostic pair
[64Cu]Cu-sartate

Published syntheses

No synthesis has been parsed for this agent yet.

Clinical literature

Clinical studies in the indexed corpus, ordered by design (multicentre, prospective, retrospective, others, case reports last) and then by year. Titles and links only, as published; this is not a summary of the evidence.

  1. 64Cu Treatment Planning and 67Cu Therapy with Radiolabeled [64Cu/67Cu]MeCOSar-Octreotate in Subjects with Unresectable Multifocal Meningioma: Initial Results for Human Imaging, Safety, Biodistribution, and Radiation Dosimetry.
    2023 · J Nucl Med · Clinical study

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Notes

Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 1 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Diagnostic pair signal at discovery: YES - Cu-64. Compound class inferred from precursor name (not stated outright) -- PMID 39911068: 'CB-TE1A1P-PEG4-LLP2A (LLP2A) was kindly provided by AusPep (34).'. Stage set/updated at stage 23 from PMID 39911068: 'We used orthotopic syngeneic (i.e., B16-F10, B78, 4T1, GL261, TH-MYCN, and E2A-PBX1) and human (i.e., SK-MEL-37, 143B, and IMR-5) cancer models for in vivo PET/CT imaging and biodistribution studies.'.
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