Tracer library / [18F]NS10743
[18F]NS10743
Also written as [18F]NS10743; [F-18]NS10743
- Radionuclide
- F-18 t½ 109.77 min
- Modality
- PET
- Production route
- —
- Stage
- Preclinical
- Syntheses indexed
- 1
What it is
- Compound class
- diazabicyclononane derivative
- Target / mechanism
- alpha7 nicotinic acetylcholine receptor (α7 nAChR) PMID 21484373
- Clinical application
- —
- Theranostic pair
- —
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| TRACERlab FX FN GE HealthCare | — | HPLC | 32.2 | ≥99 | nitro-precursor | 25464181 2015 Appl Radiat Isot TRACERlabTM FX F-N synthesis module - overall radiochemical yield of 32.2±7% (n=3) |
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Get in touchQuality control Preliminary - inferred from compound class
- Ph. Eur. monograph
- not verified No Ph. Eur. check is recorded for this entry.
- USP monograph
- not verified No USP check is recorded for this entry.
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [18F]NS10743.
Get in touchNotes
Added from reverse module search (stage 6); 1 article(s) with F-18.