Tracers / [68Ga]TATE-46

[68Ga]TATE-46

Also written as [Ga-68]Ga-TATE-46
Radionuclide
Ga-68 t½ 67.71 min
Modality
Therapy
Production route
Stage
preclinical study
Syntheses indexed
1

What it is

Compound class
Dual-target somatostatin analog-FAPI heterodimer (SSTR2/FAP-targeting peptide-quinoline conjugate)
Target / mechanism
Dual targeting of SSTR2 and FAP PMID 39770488
Clinical application
Theranostic pair

Regulatory status

FDA
EMA (centralised)
Other approvals
Brand names

Clinical use

Typical injected activity
Uptake time

Reported in the literature. Not a dosing recommendation.

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
Manual synthesisSPE>95%TATE-4639770488
2024 Pharmaceuticals (Basel)
During the labeling process, the generator was rinsed with 2 mL of 0.05 M HCl, and the waste solution was discarded.

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Notes

Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 39770488. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Stage set/updated at stage 23 from PMID 39770488: 'Preclinical Study of a Dual-Target Molecular Probe Labeled with 68Ga Targeting SSTR2 and FAP.'.