Tracer library / [68Ga]PEG6-COU

[68Ga]PEG6-COU

Also written as [Ga-68]Ga-PEG6-COU

Radionuclide: Ga-68 t½ 67.71 min
Modality: PET
Production route: —
Stage: Reported once
Syntheses indexed: 1

Preclinical only, no clinical indication yet Fibroblast activation / tumour stroma

What it is

Compound class: FAP-targeted small-molecule radiotracer with coumarin albumin binder (FAPI-based)
Target / mechanism: Fibroblast activation protein (FAP) PMID 42569132
Clinical application: Imaging of tumors via FAP overexpressed in tumor stroma (various cancers) PMID 42569132
Theranostic pair: —

Published syntheses

Module	Cassette	Purification	Yield %	RCP %	Precursor / supplier	Source
—	—	SPE	92.3%	97.4%	PEG6-COU	42569132 2026 ACS Omega

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Notes

Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 42569132. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Compound class inferred from precursor name (not stated outright) -- PMID 42569132: 'Compound PEG6-COU (m = 6): obtained as a faint yellow solid in 15.3% yield.'. | Stage 30 (2026-09-18): Modality was 'Therapy' -- a bucket value given to every agent found by the therapy-oriented bulk search (stages 21-22), not a source statement. Corrected to PET: Ga-68 is a positron emitter used only for PET imaging. Linked articles: PMID 42569132.