Tracers / [68Ga]PEG6-COU
[68Ga]PEG6-COU
Also written as [Ga-68]Ga-PEG6-COU
- Radionuclide
- Ga-68 t½ 67.71 min
- Modality
- Therapy
- Production route
- —
- Stage
- Reported once
- Syntheses indexed
- 1
What it is
- Compound class
- FAP-targeted small-molecule radiotracer with coumarin albumin binder (FAPI-based)
- Target / mechanism
- Fibroblast activation protein (FAP) PMID 42569132
- Clinical application
- Imaging of tumors via FAP overexpressed in tumor stroma (various cancers) PMID 42569132
- Theranostic pair
- —
Regulatory status
- FDA
- —
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| — | — | SPE | 92.3% | 97.4% | PEG6-COU | 42569132 2026 ACS Omega |
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Get in touchNotes
Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 42569132. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Compound class inferred from precursor name (not stated outright) -- PMID 42569132: 'Compound PEG6-COU (m = 6): obtained as a faint yellow solid in 15.3% yield.'.