Tracer library / [18F]FBAM
[18F]FBAM
Also written as [18F]FBAM; [F-18]FBAM
- Radionuclide
- F-18 t½ 109.77 min
- Modality
- PET
- Production route
- —
- Stage
- Preclinical
- Syntheses indexed
- 1
What it is
- Compound class
- Thiol-reactive prosthetic group / bifunctional 18F-labeling agent (N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide)
- Target / mechanism
- Phosphatidylserine (PS) PMID 26205076
- Clinical application
- Apoptosis imaging in murine tumor model of apoptosis (camptothecin-induced apoptosis in Jurkat cells and EL4 tumor model) PMID 26205076
- Theranostic pair
- —
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| — | — | SPE | 29±4% decay-corrected | 94-98% | — | 21507666 2011 Appl Radiat Isot was adapted to a remotely controlled synthesizer module - the final [(18)F]FBAM was obtained in a decay-corrected radiochemical yield of 29±4% (related to [(18)F]fluoride, n=12) |
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Get in touchQuality control Preliminary - inferred from compound class
- Ph. Eur. monograph
- not verified No Ph. Eur. check is recorded for this entry.
- USP monograph
- not verified No USP check is recorded for this entry.
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [18F]FBAM.
Get in touchNotes
Added from reverse module search (stage 6); 1 article(s) with F-18.