Tracers / [68Ga]Ga-BPAMD
[68Ga]Ga-BPAMD
Also written as [68Ga]Ga-BPAMD; [Ga-68]Ga-BPAMD; BPAMD; Ga-68 BPAMD
- Radionuclide
- Ga-68 t½ 67.71 min
- Modality
- PET
- Production route
- —
- Stage
- —
- Syntheses indexed
- 6
What it is
- Compound class
- DOTA-conjugated bisphosphonate
- Target / mechanism
- Bisphosphonate binding to bone mineral (hydroxyapatite) PMID 39568296
- Clinical application
- —
- Theranostic pair
- <a href="/tracers/tb161-bpamd/">tb161-bpamd</a>
Regulatory status
- FDA
- —
- EMA (centralised)
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- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| — Elysia-Raytest | vendor cassette | none | >91% | >93% | BPAMD ABX | 39568296 2024 J Labelled Comp Radiopharm GAIA® V2/LUNA® synthesis module (Elysia‐Raytest, Germany) — [68Ga]Ga‐BPAMD was obtained with > 93% RCP and > 91% RCY, in less than 25 min. |
| — Elysia-Raytest | vendor cassette | none | >91% | >93% | BPAMD ABX | 39568296 2024 J Labelled Comp Radiopharm GAIA® V2/LUNA® synthesis module (Elysia‐Raytest, Germany) — [68Ga]Ga‐BPAMD was obtained with > 93% RCP and > 91% RCY, in less than 25 min. |
| — Elysia-Raytest | vendor cassette | none | >91% | >93% | BPAMD ABX | 39568296 2024 J Labelled Comp Radiopharm GAIA® V2/LUNA® synthesis module (Elysia‐Raytest, Germany) — [68Ga]Ga‐BPAMD was produced in good radiochemical purity (> 93%) and high radiochemical yield (> 91%) using 0.3 M HEPES buffer. |
| — Elysia-Raytest | vendor cassette | none | >91% | >93% | BPAMD ABX | 39568296 2024 J Labelled Comp Radiopharm The second sequence was based on the combined GAIA®/LUNA® modules (configuration B, Figure 2C,D), lasted 23.5 min and allowed the use of different reaction vial models. — [68Ga]Ga‐BPAMD was produced in good radiochemical purity (> 93%) and high radiochemical yield (> 91%) using 0.3 M HEPES buffer. |
| — | — | — | — | — | — | 23522791 2013 Appl Radiat Isot |
| — | — | — | — | >95% | — | 27907840 2017 Nucl Med Biol without use of any synthesis module |
Need this precursor?We can point you to suppliers for [68Ga]Ga-BPAMD, or handle the enquiry for you.
Get in touchQuality control Preliminary — inferred from compound class
- Ph. Eur. monograph
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- USP monograph
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How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); radiometal tracer -> metal impurities (rule); Ga-68, generator production assumed (no synthesis data found) -> Ge-68 breakthrough (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [68Ga]Ga-BPAMD.
Get in touchNotes
Added from reverse module search (stage 6); 2 article(s) with Ga-68. Also seen with Lu-177[1] (too few articles for own row).