By indication / Bone metastases and bone lesions

Bone metastases and bone lesions

3 imaging agents and 9 therapeutic agents reported for this indication. Stage reflects how far each has been taken, not what is available in any given country.

Imaging

AgentIsotopeStageSyntheses
[18F]NaFF-18Approved12
[68Ga]Ga-BPAMD
paired with [161Tb]Tb-BPAMD
Ga-686
[89Zr]Zr-DFO-girentuximabZr-89clinical proof-of-concept / prospective pilot study4

Therapy

AgentIsotopeStageSyntheses
[223Ra]Ra-RaCl2Ra-223approved14
[153Sm]Sm-EDTMPSm-153approved10
[177Lu]Lu-LuPSMA-617Lu-177approved8
[177Lu]Lu-FAP-2286
paired with [68Ga]Ga-FAP-2286
Lu-177first-in-human4
[177Lu]Lu-BPAMD
paired with [68Ga]Ga-BPAMD
Lu-1772
[161Tb]Tb-BPAMD
paired with [68Ga]Ga-BPAMD
Tb-1611
[225Ac]Ac-DOTAZOLAc-225preclinical1
[211At]At-astatobenzamide-N-3-hydroxypropylidene-3At-211preclinical1
[153Sm]Sm-BPAMD
paired with [68Ga]Ga-BPAMD
Sm-153preclinical

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