Tracers / [188Re]Re-188-HEDP
[188Re]Re-188-HEDP
Also written as Re-188-HEDP; Re-188-Sn-HEDP
- Radionuclide
- Re-188 t½ 1020 min
- Modality
- Therapy
- Production route
- —
- Stage
- —
- Syntheses indexed
- 1
What it is
- Compound class
- bisphosphonate (HEDP)
- Target / mechanism
- —
- Clinical application
- —
- Theranostic pair
- —
Regulatory status
- FDA
- —
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| Kit-based preparation | — | — | — | >95% | HEDP kit POLATOM | 29430106 2018 Indian J Nucl Med For 188Re-HEDP, 2960–3700 MBq (80–100 mCi) ReO4- in 1–2 ml was added to the cold kit and the reconstituted solution was then heated in boiling water for 25 min. |
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Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 6 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Compound class inferred from precursor name (not stated outright) -- PMID 29430106: 'HEDP kit'.