Tracers / [68Ga]SB02055

[68Ga]SB02055

Also written as [Ga-68]Ga-SB02055
Radionuclide
Ga-68 t½ 67.71 min
Modality
Therapy
Production route
Stage
preclinical study
Syntheses indexed
1

What it is

Compound class
DOTA-conjugated (R)-pyrrolidin-2-yl-boronic acid-based FAP-targeted small molecule ligand
Target / mechanism
Fibroblast activation protein (FAP) PMID 37375746
Clinical application
Theranostic pair

Regulatory status

FDA
EMA (centralised)
Other approvals
Brand names

Clinical use

Typical injected activity
Uptake time

Reported in the literature. Not a dosing recommendation.

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
HPLC19-58%
yes
>92%SB0205537375746
2023 Pharmaceuticals (Basel)

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Notes

Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 37375746. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Stage set/updated at stage 23 from PMID 37375746: 'natGa- and 68Ga-complexes of both ligands were evaluated in preclinical studies and compared to previously reported natGa/68Ga-complexed PNT6555.'.