Tracer library / [177Lu]Lu-DOTA-r-a-ABA-CPCR4
[177Lu]Lu-DOTA-r-a-ABA-CPCR4
Also written as [Lu-177]DOTA-r-a-ABA-CPCR4
- Radionuclide
- Lu-177 t½ 9584.6 min
- Modality
- Therapy
- Production route
- —
- Stage
- —
- Syntheses indexed
- 1
What it is
- Compound class
- DOTA-conjugated CXCR4-targeting cyclic pentapeptide (CPCR4-based)
- Target / mechanism
- CXCR4 receptor targeting ligand PMID 32724470
- Clinical application
- —
- Theranostic pair
- [68Ga]Ga-DOTA-r-a-ABA-CPCR4
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| Manual synthesis | — | — | — | — | DOTA-r-a-ABA-CPCR4 | 32724470 2020 Theranostics All peptides and their respective natGa-, natLu-, natY- and natBi- complexes were synthesized in analogy to previously published protocols |
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Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 1 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Diagnostic pair signal at discovery: YES - Ga-68. Compound class inferred from precursor name (not stated outright) -- PMID 32724470: 'DOTA-r-a-ABA-CPCR4 (entry 13)'.