Tracer library / [225Ac]Ac-crown-TATE

[225Ac]Ac-crown-TATE

Also written as [Ac-225]Ac-crown-TATE

Radionuclide: Ac-225 t½ 14284.8 min
Modality: Therapy
Production route: —
Stage: —
Syntheses indexed: 0

Neuroendocrine neoplasms Preclinical only, no clinical indication yet

What it is

Compound class: somatostatin analogue peptide (crown-TATE, DOTA-TATE-type SSTR2-targeting peptide conjugate)
Target / mechanism: Somatostatin receptor 2 (SSTR2) PMID 37049918
Clinical application: Neuroendocrine tumours PMID 37049918
Theranostic pair: —

Published syntheses

No synthesis has been parsed for this agent yet.

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Notes

Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 2 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Compound class inferred from precursor name (not stated outright) -- PMID 37049918: 'crown-TATE was prepared using standardised Fmoc-based solid phase peptide synthesis (SPPS)'. Stage 26: this agent has NO own synthesis/characterisation data in the current corpus -- its only linked run(s) were unlinked (empty-quote recheck: appeared only as a control/comparator or in the wrong article).