Tracers / [213Bi]Bi-3p-C-NETA-ePSMA-16

[213Bi]Bi-3p-C-NETA-ePSMA-16

Radionuclide
Bi-213 t½ 45.6 min
Modality
Therapy
Production route
Stage
Reported once
Syntheses indexed
1

What it is

Compound class
PSMA-targeting urea-based small molecule with NETA chelator (3p-C-NETA-ePSMA-16)
Target / mechanism
PSMA (prostate-specific membrane antigen) targeting PMID 37375829
Clinical application
Theranostic pair

Regulatory status

FDA
EMA (centralised)
Other approvals
Brand names

Clinical use

Typical injected activity
Uptake time

Reported in the literature. Not a dosing recommendation.

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
Manual synthesis94%97.4 ± 2.4%3p-C-NETA-ePSMA-1637375829
2023 Pharmaceuticals (Basel)
The synthesis of [213Bi]Bi-3p-C-NETA-ePSMA-16 was performed by reacting 213BiI52− (6–12 MBq) with 3p-C-NETA-ePSMA-16 (3 nmol, 300 µL, 10 µM) at 95 °C for 7 min — [213Bi]Bi-3p-C-NETA-ePSMA-16 was obtained with excellent RCC (94%, n = 1)

Need this precursor?We can point you to suppliers for [213Bi]Bi-3p-C-NETA-ePSMA-16, or handle the enquiry for you.

Get in touch

Notes

Added at stage 22: promoted from 'Reported once' (single-article, no diagnostic pair at discovery) because a full-text synthesis with extracted data exists in parsed-therapy.xlsx -- PMID(s): 37375829. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Compound class inferred from precursor name (not stated outright) -- PMID 37375829: '3p-C-NETA-ePSMA-16 (3 nmol, 300 µL, 10 µM)'.