Tracers / [161Tb]Tb-3p-C-NETA
[161Tb]Tb-3p-C-NETA
Also written as [161Tb]Tb-3p-C-NETA; [Tb-161]Tb-3p-C-NETA
- Radionuclide
- Tb-161 t½ 9907.2 min
- Modality
- Therapy
- Production route
- —
- Stage
- —
- Syntheses indexed
- 1
What it is
- Compound class
- Somatostatin analogue peptide conjugated to NETA-derived chelator (3p-C-NETA-TATE)
- Target / mechanism
- Somatostatin receptor targeting via TATE (octreotate) peptide PMID 35966589
- Clinical application
- —
- Theranostic pair
- <a href="/tracers/ga68-3pcneta/">ga68-3pcneta</a>
Regulatory status
- FDA
- —
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| Manual synthesis | — | SPE | >95% | — | 3p-C-NETA | 35966589 2022 Theranostics 3p-C-NETA was labeled by adding... [161Tb]TbCl3: (4 MBq, 0.1M NaOAc, pH 4.1)... to the 3p-C-NETA solution... and the reaction mixture (V= 1 mL) was incubated for 12 min at the desired temperature. — a RCC of >95% was observed at 40 °C for 3p-C-NETA (10 µM) |
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Get in touchQuality control Preliminary — inferred from compound class
- Ph. Eur. monograph
- —
- USP monograph
- —
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); radiometal tracer -> metal impurities (rule); therapeutic radiopharmaceutical -> osmolality (rule); receptor ligand with a saturable target -> molar activity (rule)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [161Tb]Tb-3p-C-NETA.
Get in touchNotes
Added from reverse module search (stage 6); 2 article(s) with Tb-161.