Tracers / [18F]ADPM06

[18F]ADPM06

Also written as [18F]ADPM06; [F-18]ADPM06
Radionuclide
F-18 t½ 109.77 min
Modality
PET
Production route
Stage
Syntheses indexed
1

What it is

Compound class
BF2-chelated tetraaryl-azadipyrromethene photosensitizer
Target / mechanism
Clinical application
Theranostic pair

Regulatory status

FDA
EMA (centralised)
Other approvals
Brand names

Clinical use

Typical injected activity
Uptake time

Reported in the literature. Not a dosing recommendation.

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
COSMiC-Compact
NMP Business Support
HPLC13 ± 2.7%
yes
> 95%ADPM06
BOC Sciences
37458904
2023 EJNMMI Radiopharm Chem
[18F]ADPM06 was synthesized using a COSMiC-Compact Synthesizer (NMP Business Support Company, Sanda, Japan). — The decay-corrected radiochemical yield from [18F]F− at the start of synthesis was 13 ± 2.7% (n = 5).

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Quality control Preliminary — inferred from compound class

Ph. Eur. monograph
USP monograph
AppearancepHRCP HPLCRCP TLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 1 article(s) with F-18.