Tracer library / [131I]FAPI

[131I]FAPI

Also written as I-131-FAPI

Radionuclide: I-131 t½ 11549 min
Modality: Therapy
Production route: —
Stage: Preclinical
Syntheses indexed: 0

Glioma and brain tumours Preclinical only, no clinical indication yet

What it is

Compound class: FAP inhibitor (FAPI) radiolabeled small molecule
Target / mechanism: Fibroblast activation protein (FAP) PMID 39281380
Clinical application: Tumor-targeted diagnosis and therapy of cancer-associated fibroblasts in malignant epithelial tumors PMID 39281380
Theranostic pair: [68Ga]Ga-FAPI

Published syntheses

No synthesis has been parsed for this agent yet.

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Notes

Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 2 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Diagnostic pair signal at discovery: YES - Ga-68. Stage set/updated at stage 39 from PMID 39281380: 'The aim of this study was to radiosynthesize a novel molecular probe 131I-FAPI and evaluate its in-vitro targeting and biological characteristics.'.