By indication / Glioma and brain tumours
Glioma and brain tumours
15 imaging agents and 10 therapeutic agents reported for this indication. Stage reflects how far each has been taken, not what is available in any given country.
Imaging
| Agent | Isotope | Stage | Syntheses |
|---|---|---|---|
| [18F]FDOPA | F-18 | Approved | 49 |
| [18F]FET | F-18 | Clinical research | 23 |
| [11C]methionine | C-11 | — | 13 |
| [18F]FETrp | F-18 | Research | 5 |
| [18F]FPIA | F-18 | Clinical research | 4 |
| [18F]PBR111 | F-18 | — | 3 |
| [18F]F-PSMA-617-NODA | F-18 | — | 2 |
| [18F]F-PSMA-617-RESCA | F-18 | — | 2 |
| [11C]PD153035 | C-11 | investigational (evaluated in patients, pilot clinical studies) | 1 |
| [18F]AG-120 | F-18 | preclinical study | 1 |
| [18F]BIBD-239 | F-18 | first-in-human | 1 |
| [18F]FB-2BD42 | F-18 | — | 1 |
| [18F]ef5 | F-18 | — | |
| [18F]fluorophenylalanine | F-18 | first-in-human | |
| [18F]L-Glutamic | F-18 | investigational |
Therapy
| Agent | Isotope | Stage | Syntheses |
|---|---|---|---|
| [131I]iodine | I-131 | — | 3 |
| [177Lu]Lu-DOTA-DV1-K-DV3 | Lu-177 | — | 2 |
| [225Ac]Ac-FAPI-46 paired with [68Ga]Ga-FAPI-46 | Ac-225 | preclinical study | 1 |
| [67Ga]Comb-2 | Ga-67 | Reported once | 1 |
| [177Lu]Lu-Comb-2 | Lu-177 | Reported once | 1 |
| [177Lu]Lu-DOTA-POL3026 | Lu-177 | Reported once | 1 |
| [99mTc]Tc(CO)3-GRGDHV | Tc-99m | Reported once | 1 |
| [124I]PN67 paired with [131I]PN67 | I-124 | Reported once | 1 |
| [225Ac]Ac-Pep-1L paired with [64Cu]Pep-1L | Ac-225 | Reported once | 1 |
| [64Cu]Pep-1L paired with [225Ac]Ac-Pep-1L | Cu-64 | Reported once | 1 |
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