Tracer library / [131I]I-131-VAT

[131I]I-131-VAT

Also written as I-131-VAT

Radionuclide: I-131 t½ 11549 min
Modality: Therapy
Production route: —
Stage: Preclinical
Syntheses indexed: 1

Glioma and brain tumours

What it is

Compound class: Disintegrin (snake venom protein, Vipera anatolica crude venom)
Target / mechanism: Integrin binding PMID 30276529
Clinical application: Glioblastoma imaging PMID 30276529
Theranostic pair: [18F]VAT

Published syntheses

Module	Cassette	Purification	Yield %	RCP %	Precursor / supplier	Source
Manual synthesis n/a	—	—	—	—	VAT crude venom	30276529 2019 Appl Biochem Biotechnol VAT crude venom and echistatin were labeled with 131I via iodogen method.

Need this precursor?We can point you to suppliers for [131I]I-131-VAT, or handle the enquiry for you.

Get in touch

Notes

Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 1 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. Diagnostic pair signal at discovery: YES - F-18. Compound class inferred from precursor name (not stated outright) -- PMID 30276529: 'VAT crude venom and echistatin were labeled with 131I via iodogen method.'. Stage set/updated at stage 39 from PMID 30276529: 'Intracellular uptakes of radiolabeled molecules were investigated in U87MG cell line.'.