Tracers / [18F]FBPA
[18F]FBPA
Also written as [18F]FBPA; [F-18]FBPA; FBPA
- Radionuclide
- F-18 t½ 109.77 min
- Modality
- PET
- Production route
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- Stage
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- Syntheses indexed
- 6
What it is
- Compound class
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- Target / mechanism
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- Clinical application
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- Theranostic pair
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Regulatory status
- FDA
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- EMA (centralised)
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- Other approvals
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- Brand names
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Clinical use
- Typical injected activity
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- Uptake time
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Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| In-house / custom built | — | — | — | — | — | 27744544 2017 Ann Nucl Med Radiosynthesis of 18F-FBPA is described in the Supplementary data. |
| — | — | — | 8.5±2.0% | 98±1% | 4-borono-L-phenylalanine | 26159661 2015 Appl Radiat Isot a modified nucleophilic GE TRACERlab FXFDG — a RCY of 8.5±2.0% |
| — | — | — | 15.5% ± 6.3% yes | — | spirocyclic iodonium ylide (SCIDY) precursor | 42429632 2026 Mol Pharm using a spirocyclic iodonium ylide (SCIDY) precursor on a commercial module — decay-corrected radiochemical yield of 15.5% ± 6.3% |
| — | — | — | 2.6% no | — | BNBA | 42365564 2026 EJNMMI Radiopharm Chem |
| — | — | — | 0.3% no | — | P-02 | 42365564 2026 EJNMMI Radiopharm Chem |
| — | — | — | 3.1% no | — | P-03 | 42365564 2026 EJNMMI Radiopharm Chem |
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Get in touchQuality control Preliminary — inferred from compound class
- Ph. Eur. monograph
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- USP monograph
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How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [18F]FBPA.
Get in touchNotes
Added from reverse module search (stage 6); 2 article(s) with F-18.