Tracer library / [177Lu]Lu-DOTA-2P(FAPI)2

[177Lu]Lu-DOTA-2P(FAPI)2

Also written as [Lu-177]Lu-DOTA-2P(FAPI)2; Lu-177-DOTA-2P(FAPI)2
Radionuclide
Lu-177 t½ 9584.6 min
Modality
Therapy
Production route
—
Stage
Preclinical
Syntheses indexed
0
Hepatobiliary and pancreatic cancerFibroblast activation / tumour stroma

What it is

Compound class
FAP inhibitor homodimer radioligand (FAPi dimer)
Target / mechanism
Fibroblast activation protein (FAP) PMID 35917335
Clinical application
FAP-positive hepatocellular carcinoma and malignant tumors (preclinical PDX/CDX models) PMID 35917335
Theranostic pair
—

Published syntheses

No synthesis has been parsed for this agent yet.

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Notes

Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 2 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty.
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