Tracer library / [18F]FDR
[18F]FDR
Also written as [18F]FDR
- Radionuclide
- F-18 t½ 109.77 min
- Modality
- PET
- Production route
- —
- Stage
- Preclinical
- Syntheses indexed
- 0
What it is
- Compound class
- 5-fluoro-5-deoxy-ribose (fluoroglycosylation prosthetic group) conjugated to RGD peptide
- Target / mechanism
- αvβ3 integrin receptor PMID 23733207
- Clinical application
- —
- Theranostic pair
- —
Published syntheses
No synthesis has been parsed for this agent yet.
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Get in touchQuality control Preliminary - inferred from compound class
- Ph. Eur. monograph
- not verified No Ph. Eur. check is recorded for this entry.
- USP monograph
- not verified No USP check is recorded for this entry.
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [18F]FDR.
Get in touchNotes
Added from reverse module search (stage 6); 1 article(s) with F-18. Stage set/updated at stage 39 from PMID 23733207: 'the conjugated RGD peptides showed selectivity for PC3 cells, which express αvβ3 integrin, with the c(RGDfK)-Aoa-[(18)F]FDR demonstrating better binding'.