Tracer library / 2-[18F]fluoro-myo-inositol

2-[18F]fluoro-myo-inositol

Also written as 2-[18F]fluoro-myo-inositol
Radionuclide
F-18 t½ 109.77 min
Modality
PET
Production route
—
Stage
Preclinical
Syntheses indexed
0

What it is

Compound class
radiolabelled inositol (fluorinated myo-inositol analogue)
Target / mechanism
Inositol uptake/transport related to membrane lipid metabolism and mitogenic signaling PMID 22944120
Clinical application
Human breast cancer xenograft model PMID 22944120
Theranostic pair
—

Published syntheses

No synthesis has been parsed for this agent yet.

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph
not verified No Ph. Eur. check is recorded for this entry.
USP monograph
not verified No USP check is recorded for this entry.
AppearancepHRCP HPLCRCP TLCHPLC cond.Radionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrity
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); weak UV chromophore (sugar/simple ion/short-chain acid) -> conductometric detection (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 2 article(s) with F-18. Stage 26: this agent has NO own synthesis/characterisation data in the current corpus -- its only linked run(s) were unlinked (empty-quote recheck: appeared only as a control/comparator or in the wrong article).
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