Tracers / [11C]KIn83
[11C]KIn83
Also written as [11C]KIn83; [C-11]KIn83
- Radionuclide
- C-11 t½ 20.36 min
- Modality
- PET
- Production route
- —
- Stage
- —
- Syntheses indexed
- 1
What it is
- Compound class
- 3-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-dibenzo[b,d]thiophene 5,5-dioxide derivative (α7-nAChR radioligand)
- Target / mechanism
- α7 nicotinic acetylcholine receptor (α7-nAChR) radioligand PMID 40142141
- Clinical application
- —
- Theranostic pair
- —
Regulatory status
- FDA
- —
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| TRACERlab FX2 C GE HealthCare | — | HPLC+SPE | 622 MBq average yield | >95% | desmethyl precursor (3-(1,4-diazabicyclo [3.2.2]nonan-4-yl)-6-hydroxyl-dibenzo[b,d] thiophene 5,5-dioxide) Syngene International Ltd., India | 40142141 2025 Molecules a fully automated GMP-complaint synthesizer, "TRACERlab FX2 C Synthesizer", supplied by GE — The average yield of the process was 622 MBq (650 MBq, 697 MBq, and 520 MBq, respectively) |
Need this precursor?We can point you to suppliers for [11C]KIn83, or handle the enquiry for you.
Get in touchQuality control Preliminary — inferred from compound class
- Ph. Eur. monograph
- —
- USP monograph
- —
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [11C]KIn83.
Get in touchNotes
Added from reverse module search (stage 6); 1 article(s) with C-11. Compound class inferred from precursor name (not stated outright) -- PMID 40142141: 'Syngene International Ltd., India, supplied the corresponding desmethyl precursor (3-(1,4-diazabicyclo [3.2.2]nonan-4-yl)-6-hydroxyl-dibenzo[b,d] thiophene 5,5-dioxide)'.