Tracers / [18F]fluoro-3-(2(S)-azetidinylmethoxy)pyridine
[18F]fluoro-3-(2(S)-azetidinylmethoxy)pyridine
Also written as [18F]Fluoro-3-(2(S)-azetidinylmethoxy)pyridine; [F-18]Fluoro-3-(2(S)-azetidinylmethoxy)pyridine
- Radionuclide
- F-18 t½ 109.77 min
- Modality
- PET
- Production route
- —
- Stage
- —
- Syntheses indexed
- 0
What it is
- Compound class
- PET radioligand (fluorinated nicotine analogue, azetidinylmethoxypyridine derivative)
- Target / mechanism
- α4β2* nicotinic acetylcholine receptors (nAChRs) PMID 35130968
- Clinical application
- Older adults with mild cognitive impairment and Alzheimer's disease dementia PMID 35130968
- Theranostic pair
- —
Regulatory status
- FDA
- —
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
No synthesis has been parsed for this agent yet.
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Get in touchQuality control Preliminary — inferred from compound class
- Ph. Eur. monograph
- —
- USP monograph
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How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary); conventional nucleophilic 18F-fluorination assumed from isotope/compound class, no synthesis data confirming K222 use -> Kryptofix test (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [18F]fluoro-3-(2(S)-azetidinylmethoxy)pyridine.
Get in touchNotes
Added from reverse module search (stage 6); 1 article(s) with F-18. | Stage 28: added indication(s) psy-schizophrenia, psy-addiction from consolidated missing-rubric review.