Tracer library / [68Ga]Ga-D0103

[68Ga]Ga-D0103

Also written as D0103; Ga-68 D0103; Ga-68-D0103

Radionuclide: Ga-68 t½ 67.71 min
Modality: PET
Production route: —
Stage: —
Syntheses indexed: 0

Gastrointestinal and colorectal cancer Receptor expression phenotyping

What it is

Compound class: αvβ6-integrin-targeting peptide (D0103)
Target / mechanism: αvβ6-integrin (ITGB6) targeting PMID 40540027
Clinical application: PET/CT imaging of esophageal squamous cell carcinoma for re-staging and therapy guidance PMID 40540027
Theranostic pair: —

Published syntheses

No synthesis has been parsed for this agent yet.

Clinical literature

Clinical studies in the indexed corpus, ordered by design (multicentre, prospective, retrospective, others, case reports last) and then by year. Titles and links only, as published; this is not a summary of the evidence.

PET/CT imaging of esophageal cancer targeting tumor cell specific αvβ6-integrin expression.
2025 · Eur J Nucl Med Mol Imaging · Clinical study

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph: not verified No Ph. Eur. check is recorded for this entry.
USP monograph: not verified No USP check is recorded for this entry.

AppearancepHRCP HPLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrityMolar activityMetal impuritiesGe-68 breakthrough

How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); radiometal tracer -> metal impurities (rule); Ga-68, generator production assumed (no synthesis data found) -> Ge-68 breakthrough (preliminary); receptor ligand with a saturable target -> molar activity (rule)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 1 article(s) with Ga-68. Compound class inferred from precursor name (not stated outright) -- PMID 40540027: 'The radiolabeling precursors Trivehexin and D0103 were synthesized according to previously published protocols'.