By indication / Gastrointestinal and colorectal cancer
Gastrointestinal and colorectal cancer
5 imaging agents and 11 therapeutic agents reported for this indication. Stage reflects how far each has been taken, not what is available in any given country.
Imaging
| Agent | Isotope | Stage | Syntheses |
|---|---|---|---|
| [18F]AlF-FAPI-74 | F-18 | — | 10 |
| [89Zr]Zr-DFO-girentuximab | Zr-89 | clinical proof-of-concept / prospective pilot study | 4 |
| [68Ga]Ga-D0103 | Ga-68 | — | 1 |
| [18F]L-Glutamic | F-18 | investigational | |
| [68Ga]Ga-FAPI-74 | Ga-68 | — |
Therapy
| Agent | Isotope | Stage | Syntheses |
|---|---|---|---|
| [90Y]Y-microsphere | Y-90 | approved | 11 |
| [177Lu]Lu-DOTA-trastuzumab | Lu-177 | clinical evaluation | 5 |
| [177Lu]Lu-FAP-2286 paired with [68Ga]Ga-FAP-2286 | Lu-177 | first-in-human | 4 |
| [225Ac]Ac-225-PRIT | Ac-225 | preclinical study | 3 |
| [177Lu]Lu-girentuximab | Lu-177 | — | 2 |
| [177Lu]Lu-Gemini | Lu-177 | — | 2 |
| [68Ga]HNI01 | Ga-68 | Reported once | 1 |
| [64Cu]SarAr-PEG10-Tz paired with [67Cu]Cu-SarAr-PEG10-Tz | Cu-64 | Reported once | 1 |
| [67Cu]Cu-SarAr-PEG10-Tz paired with [64Cu]SarAr-PEG10-Tz | Cu-67 | Reported once | 1 |
| [68Ga]CE-21 paired with [177Lu]Lu-CE-21 | Ga-68 | first-in-human | 1 |
| [177Lu]Lu-DTPA-anti-TRA | Lu-177 | preclinical |
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