Tracers / [90Y]Y-microsphere
[90Y]Y-microsphere
Also written as [Y-90]microsphere; Y-90-Microsphere; Y-90-TARE; Y-90-SIRT; [Y-90]Yttria; [Y-90]yttria
- Radionuclide
- Y-90 t½ 3843.6 min
- Modality
- Therapy
- Production route
- —
- Stage
- approved
- Syntheses indexed
- 11
What it is
- Compound class
- Yttrium-90 microspheres (radioembolization microspheres)
- Target / mechanism
- —
- Clinical application
- Selective internal radiation treatment (SIRT) / transarterial radioembolization for liver tumours (primary and metastatic liver cancer) PMID 24036875
- Theranostic pair
- —
Regulatory status
- FDA
- —
- EMA (centralised)
- —
- Other approvals
- —
- Brand names
- —
Clinical use
- Typical injected activity
- —
- Uptake time
- —
Reported in the literature. Not a dosing recommendation.
Published syntheses
| Module | Cassette | Purification | Form | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|---|
| — | — | — | — | — | — | — | 37226091 2023 BMC Gastroenterol |
| — | — | — | resin | — | — | — | 24036875 2013 J Appl Clin Med Phys |
| — | — | — | resin | — | — | — | 42476033 2026 Nucl Med Biol |
| — | — | — | — | — | — | — | 42359903 2026 Anal Methods |
| — | — | — | resin | — | — | — | 42263447 2026 Nucl Med Biol |
| — | — | — | — | — | — | — | 42230138 2026 J Neurointerv Surg |
| — | — | — | resin | — | — | — | 42203908 2026 Cardiovasc Intervent Radiol |
| — | — | — | resin | — | — | — | 41842669 2026 Radiology |
| — | — | — | glass | — | — | — | 41842669 2026 Radiology |
| — | — | — | resin | — | — | — | 41217471 2026 Eur J Nucl Med Mol Imaging |
| — | — | — | resin | — | — | — | 40762798 2026 Eur J Nucl Med Mol Imaging |
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Added at stage 21 from therapy-discovered.xlsx (bulk PubMed search by isotope/therapy-type/known-agent, not individually researched yet) -- 2 articles found. Target/mechanism, clinical application, indications, approval and precursor fields still need per-agent research and are intentionally left empty. | Stage 29 (2026-09-14): merged y90-tare, y90-sirt, y90-yttria into this row per user decision -- TARE/SIRT are procedure names (trans-arterial radioembolization / selective internal radiation therapy) and 'yttria' names the carrier material of the glass-type microsphere, not separate substances; resin vs glass is now tracked per-run in the parsed files' new 'Formulation / carrier' field (resin/glass/not stated), not as separate agents -- same isotope, same therapeutic principle, different carrier. One PMID from the y90-tare discovery cluster (33529007, 'Iodine-131 Microbeads...') was never actually about this agent -- it was never linked in any parsed file or corpus Tracer key, so nothing needed unlinking.