Tracer library / [68Ga]Ga-EMP100

[68Ga]Ga-EMP100

Also written as [68Ga]Ga-EMP100; [Ga-68]Ga-EMP100

Radionuclide: Ga-68 t½ 67.71 min
Modality: PET
Production route: —
Stage: —
Syntheses indexed: 1

Receptor expression phenotyping

What it is

Compound class: Cyclic oligopeptide conjugated to DOTA chelator (c-MET-targeting peptide)
Target / mechanism: c-MET (transmembrane receptor) PMID 37843660
Clinical application: PET-CT imaging of lesions expressing c-MET in cancer PMID 37843660
Theranostic pair: —

Published syntheses

Module	Cassette	Purification	Yield %	RCP %	Precursor / supplier	Source
— Elysia-Raytest	vendor cassette	SPE	75% 72%, 75% not corrected	99.08% 99.45%, 99.81%	EMP100 peptide Edinburgh Molecular Imaging	37843660 2023 EJNMMI Radiopharm Chem The automated synthesis of [68Ga]Ga-EMP100 was performed on the GAIA synthesis module (Elysia Raytest, Belgium) - RCY (n.d.c.)GAIA report> 50%75%72%75%

Precursor

Common precursor: —
Suppliers seen in the literature: —
Cited suppliers in indexed syntheses: Edinburgh Molecular Imaging
Typical final purification: —

Need this precursor?We can point you to suppliers for [68Ga]Ga-EMP100, or handle the enquiry for you.

Get in touch

Quality control Preliminary - inferred from compound class

Ph. Eur. monograph: not verified No Ph. Eur. check is recorded for this entry.
USP monograph: not verified No USP check is recorded for this entry.

AppearancepHRCP HPLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrityMolar activityMetal impuritiesGe-68 breakthrough

How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); radiometal tracer -> metal impurities (rule); Ga-68, generator production assumed (no synthesis data found) -> Ge-68 breakthrough (preliminary); receptor ligand with a saturable target -> molar activity (rule)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

Setting up quality control?We can help you scope the equipment needed to release [68Ga]Ga-EMP100.

Get in touch

Notes

Added from reverse module search (stage 6); 1 article(s) with Ga-68.