Tracer library / [11C]AZ13198083
[11C]AZ13198083
Also written as [11C]AZ13198083; [C-11]AZ13198083
- Radionuclide
- C-11 t½ 20.36 min
- Modality
- PET
- Production route
- —
- Stage
- —
- Syntheses indexed
- 2
What it is
- Compound class
- histamine type-3 receptor ligand
- Target / mechanism
- Histamine type-3 receptor (H3R) PMID 32588452
- Clinical application
- —
- Theranostic pair
- —
Published syntheses
| Module | Cassette | Purification | Yield % | RCP % | Precursor / supplier | Source |
|---|---|---|---|---|---|---|
| In-house / custom built | — | HPLC+SPE | 71 decay-corrected | >99% | — | 32588452 2020 J Labelled Comp Radiopharm we here report the development of a novel, user\u2010friendly, fully automated, and good manufacturing practice (GMP) compliant low\u2010pressure synthesis module for 11C\u2010carbonylation reactions using [11C]CO - an overall radiochemical yield (RCY) of 71% |
| TracerMaker Scansys Laboratorieteknik | — | HPLC+SPE | — | — | — | 37513867 2023 Pharmaceuticals (Basel) TracerMaker™, which is an all-in-one 11C-chemistry module that allows for the 11C-labeling of terminal methyl groups using standard 11C-methylation as well as the radiolabeling of the carbonyl moiety using either [11C]CO2 or [11C]CO |
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Get in touchQuality control Preliminary - inferred from compound class
- Ph. Eur. monograph
- not verified No Ph. Eur. check is recorded for this entry.
- USP monograph
- not verified No USP check is recorded for this entry.
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); organic-phase radiosynthesis assumed from isotope/compound class, no synthesis data confirming it -> GC residual solvents (preliminary)
Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived
Setting up quality control?We can help you scope the equipment needed to release [11C]AZ13198083.
Get in touchNotes
Added from reverse module search (stage 6); 1 article(s) with C-11.