Tracer library / [68Ga]Ga-oxine

[68Ga]Ga-oxine

Also written as [68Ga]Ga-oxine; [68Ga]oxine; [Ga-68]Ga-oxine; [Ga-68]oxine

Radionuclide: Ga-68 t½ 67.71 min
Modality: PET
Production route: —
Stage: Clinical research
Syntheses indexed: 0

Dosimetry and biodistribution studies

What it is

Compound class: 8-Hydroxyquinoline (oxine) complex - cell/RBC labeling agent
Target / mechanism: —
Clinical application: PET/CT imaging of the spleen using gallium-oxine-labeled, heat-damaged red blood cells for differentiation of splenic from non-splenic tissue and diagnosis of splenic anomalies PMID 36766669
Theranostic pair: —

Published syntheses

No synthesis has been parsed for this agent yet.

Clinical literature

Clinical studies in the indexed corpus, ordered by design (multicentre, prospective, retrospective, others, case reports last) and then by year. Titles and links only, as published; this is not a summary of the evidence.

PET/CT of the Spleen with Gallium-Oxine-Labeled, Heat-Damaged Red Blood Cells: Clinical Experience and Technical Aspects.
2023 · Diagnostics (Basel) · Clinical study

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Quality control Preliminary - inferred from compound class

Ph. Eur. monograph: not verified No Ph. Eur. check is recorded for this entry.
USP monograph: not verified No USP check is recorded for this entry.

AppearancepHRCP HPLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrityMetal impuritiesGe-68 breakthrough

How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); radiometal tracer -> metal impurities (rule); Ga-68, generator production assumed (no synthesis data found) -> Ge-68 breakthrough (preliminary)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 2 article(s) with Ga-68. Stage set/updated at stage 39 from PMID 36766669: 'Ten patients underwent [68Ga]gallium-oxine-RBC-PET/CT for the classification of eleven unclear lesions (3 intra-, 8 extrapancreatic).'.