Tracers / [68Ga]Ga-P16-093

[68Ga]Ga-P16-093

Also written as [68Ga]Ga-P16-093; [Ga-68]Ga-P16-093
Radionuclide
Ga-68 t½ 67.71 min
Modality
PET
Production route
Stage
Phase 2 clinical trial
Syntheses indexed
1

What it is

Compound class
Small molecule PSMA-targeting PET radioligand (O-(carboxymethyl)-L-tyrosine scaffold with HBED-CC chelator)
Target / mechanism
Prostate-specific membrane antigen (PSMA) PMID 35349040
Clinical application
Prostate cancer patients, including newly diagnosed primary disease and biochemical recurrence PMID 41366119
Theranostic pair

Regulatory status

FDA
EMA (centralised)
Other approvals
Brand names

Clinical use

Typical injected activity
Uptake time

Reported in the literature. Not a dosing recommendation.

Published syntheses

ModuleCassettePurificationYield %RCP %Precursor / supplierSource
42418373
2026 J Med Chem

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Quality control Preliminary — inferred from compound class

Ph. Eur. monograph
USP monograph
AppearancepHRCP HPLCHPLC UVRadionuclidic (HPGe)Half-lifeActivityEndotoxins (LAL)SterilityFilter integrityMolar activityMetal impuritiesGe-68 breakthrough
How this set was arrived at. base set per Ph. Eur. general monograph 0125 (rule); radiometal tracer -> metal impurities (rule); Ga-68, generator production assumed (no synthesis data found) -> Ge-68 breakthrough (preliminary); receptor ligand with a saturable target -> molar activity (rule)

Tests listed by reference only. Monograph texts are copyrighted and are not reproduced here. How these are derived

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Notes

Added from reverse module search (stage 6); 3 article(s) with Ga-68.